Pathogenesis of effects of exposure to atmospheric pollutants during pregnancy on infant allergic diseases

doi:10.11852/zgetbjzz2017-25-09-15

Abstract

Abstract: The pregnant period is the most important one in our whole life.According to the literature in western countries,the allergic diseases may be induced by the air pollution which could mediated by the fetal developmental programming.Therefore,this article review the pathogensis and correlation between exposure to air pollutants and allergic diseases,in order to provide clues for the prevention and treatment of these diseases.

Key words: pregnancy, air pollution, allergic disease, pathogenesis

摘要： 孕期是孕育生命的关键期,研究表明,大气污染物可改变胎儿的发育编程,导致过敏性疾病的发生。本文就孕期大气污染暴露与过敏性疾病的关系及其发病机制做一综述,以期对婴幼儿过敏性疾病的防治提供理论依据。

关键词: 孕期, 大气污染, 过敏性疾病, 发病机制

CLC Number:

R179

CHEN Zhen-jiang,GU Gui-xiong,HUA Jing. Pathogenesis of effects of exposure to atmospheric pollutants during pregnancy on infant allergic diseases[J]. journal1, 2017, 25(9): 914-913.

陈振江,古桂雄,花静. 孕期大气污染物暴露对婴幼儿过敏性疾病影响的发病机制[J]. 中国儿童保健杂志, 2017, 25(9): 914-913.

0
/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://manu41.magtech.com.cn/Jwk_zgetbjzz/EN/10.11852/zgetbjzz2017-25-09-15

https://manu41.magtech.com.cn/Jwk_zgetbjzz/EN/Y2017/V25/I9/914

References

[1] 王硕,蒋竞雄,王燕,等.城市0~24月龄婴幼儿过敏性疾病症状流行病学调查[J].中国儿童保健杂志,2016,24(2):119-122.
[2] Clark NA,Demers PA,Karr CJ,et al.Effect of early life exposure to air pollution on development of childhood asthma[J].Environ Health Perspect,2010,118(2):284-290.
[3] Miyake Y,Tanaka K,Fujiwara H,et al.Residential proximity to main roads during pregnancy and the risk of allergic disorders in Japanese infants:the Osaka maternal and child health study[J].Pediatric Allergy and Immunology,2010,21(1 Pt 1):22-28.
[4] Stelmach I,Majak P,Jerzynska J,et al.The effect of prenatal exposure to phthalates on food allergy and early eczema in inner-city children[J].Allergy and Asthma Proceedings,2015,36(4):72-78.
[5] McBride D,Keil T,Grabenhenrich L,et al.The EuroPrevall birth cohort study on food allergy:baseline characteristics of 12,000 newborns and their families from nine European countries[J].Pediatric Allergy and Immunology,2012,23(3):230-239.
[6] Raherison C,Pénard-Morand C,Moreau D,et al.Smoking exposure and allergic sensitization in children according to maternal allergies[J].Annals of Allergy,Asthma & Immunology,Asthma,& Immunology,2008,100(4):351-357.
[7] Just AC,Whyatt RM,Perzanowski MS,et al.Prenatal exposure to butylbenzyl phthalate and early eczema in an urban cohort[J].Environmental Health Perspectives,2012,120(10):1475-1480.
[8] Deng Q,Lu C,Ou C,et al.Preconceptional,prenatal and postnatal exposure to outdoor and indoor environmental factors on allergic diseases/symptoms in preschool children[J].Chemosphere,2016,152:459-467.
[9] Zhao Z,Zhang X,Liu R,et al.Prenatal and early life home environment exposure in relation to preschool children's asthma,allergic rhinitis and eczema in Taiyuan,China[J].Chinese Science Bulletin,2013,58(34):4245-4251.
[10] Aguilera I,Pedersen M,Garcia-Esteban R,et al.Early-life exposure to outdoor air pollution and respiratory health,ear infections,and eczema in infants from the INMA study[J].Environmental Health Perspectives,2013,121(3):387-392.
[11] Jedrychowski W,Perera F,Maugeri U,et al.Effects of prenatal and perinatal exposure to fine air pollutants and maternal fish consumption on the occurrence of infantile eczema[J].International Archives of Allergy and Immunology,2011,155(3):275-281.
[12] Patel MM,Quinn JW,Jung KH,et al.Traffic density and stationary sources of air pollution associated with wheeze,asthma,and immunoglobulin E from birth to age 5 years among New York City children[J].Environmental Research,2011,111(8):1222-1229.
[13] Lee SL,Lam TH,Leung TH,et al.Foetal exposure to maternal passive smoking is associated with childhood asthma,allergic rhinitis,and eczema[J].The Scientific World Journal,2012,2012:542983.
[14] Neuman A,Hohmann C,Orsini N,et al.Maternal smoking in pregnancy and asthma in preschool children:a pooled analysis of eight birth cohorts[J].Am J Respir Crit Care Med,2012,186(10):1037-1043.
[15] Magnus MC,Haberg SE,Karlstad O,et al.Grandmother's smoking when pregnant with the mother and asthma in the grandchild:the Norwegian mother and child cohort study[J].Thorax,2015,70(3):237-243.
[16] Tanaka K,Miyake Y.Association between prenatal and postnatal tobacco smoke exposure and allergies in young children[J].The Journal of Asthma,2011,48(5):458-463.
[17] Thacher JD,Gruzieva O,Pershagen G,et al.Pre- and postnatal exposure to parental smoking and allergic disease through adolescence[J].Pediatrics,2014,134(3):428-434.
[18] Janssen BG,Godderis L,Pieters N,et al.Placental DNA hypomethylation in association with particulate air pollution in early life[J].Particle & Fibre Toxicology,2013,10(1):22.
[19] Wang IJ,Chen SL,Lu TP,et al.Prenatal smoke exposure,DNA methylation,and childhood atopic dermatitis[J].Clinical and Experimental Allergy,2013,43(5):535-543.
[20] Wilhelm-Benartzi CS,Houseman EA,Maccani MA,et al.In utero exposures,infant growth,and DNA methylation of repetitive elements and developmentally related genes in human placenta[J].Environmental Health Perspectives,2012,120(2):296-302.
[21] Sharma S,Litonjua A.Asthma,allergy,and responses to methyl donor supplements and nutrients[J].The Journal of Allergy and Clinical Immunology,2014,133(5):1246-1254.
[22] Ibrahimou B,Salihu HM,Aliyu MH,et al.Risk of preeclampsia from exposure to particulate matter (PM_2.5) speciation chemicals during pregnancy[J].Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine,2014,56(12):1228-1234.
[23] De Melo JO,Soto SF,Katayama IA,et al.Inhalation of fine particulate matter during pregnancy increased IL-4 cytokine levels in the fetal portion of the placenta[J].Toxicology Letters,2015,232(2):475-480.
[24] Strachan DP.Family size,infection and atopy:the first decade of the "hygiene hypothesis"[J].Thorax,2000,55 (Suppl 1):2-10.
[25] Dominguez-Bello MG,Costello EK,Contreras M,et al.Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns[J].Proceedings of the National Academy of Sciences of the United States of America,2010,107(26):11971-11975.
[26] Salim SY,Kaplan GG,Mad KL.Air pollution effects on the gut microbiota:a link between exposure and inflammatory disease[J].Gut Microbes,2014,5(2):215-219.
[27] Pendse M,Hooper LV.Mum's microbes boost baby's immunity[J].Nature,2016,533(7601):42-43.
[28] Round JL,Lee SM,Li J,et al.The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota[J].Science,2011,332(6032):974-977.