journal1 ›› 2018, Vol. 26 ›› Issue (5): 510-512.DOI: 10.11852/zgetbjzz2018-26-05-13

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Research progress on the relationship between air pollution and mechanism of asthma in children

YUE Chun-lan, TIAN Zhi-liang   

  1. The Second Affiliated Hospital of Harbin Medical University, Haerbin, Heilongjiang 150000,China
  • Received:2017-10-28 Online:2018-05-10 Published:2018-05-10
  • Contact: TIAN Zhi-liang,


岳春兰, 田执梁   

  1. 哈尔滨医科大学附属第二医院,黑龙江 哈尔滨 150000
  • 通讯作者: 田执梁,
  • 作者简介:岳春兰(1990-),女,山东人,硕士学位,主要研究方向为儿童呼吸系统疾病。

Abstract: At present,the smog is serious and the air is of poor quality in many parts of China.The causes of air pollution are complicated.The sources of atmospheric particulates are more complex and variable. A wide variety of air pollutants are common, such as traffic related air pollutants, polycyclic aromatic hydrocarbons, cigarette smoke, dust particles and fine particles PM 2.5. And these pollutants are all closely related to childhood asthma. However, the toxic components and toxic mechanisms of them have not been confirmed.In addition, the health effects and toxicological mechanisms have become one of the hot issues in the scientific frontier.In this paper, the mechanism of air pollution on causing or aggravating asthma in children in recent years was analyzed comprehensively.

Key words: air pollution, childhood asthma, airborne particulate matter, apparent genome

摘要: 我国多地区雾霾严重,空气质量堪忧。大气污染成因复杂,大气颗粒物的来源更为复杂多变。常见的空气污染物种类繁多,如交通相关空气污染物、多环芳香烃、香烟烟雾、尘埃颗粒及细颗粒物 PM2.5,均与儿童哮喘密切相关,其毒性组分和致毒机制尚不明确,健康效应和毒理机制已经成为前沿的科学热点问题之一。本文就近几年来关于空气污染加重或引起儿童哮喘的机制进行综合分析。

关键词: 空气污染, 儿童哮喘, 大气颗粒物, 表观基因组

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