journal1 ›› 2018, Vol. 26 ›› Issue (8): 862-864.DOI: 10.11852/zgetbjzz2018-26-08-14

Previous Articles     Next Articles

Research progress on the correlation between protein gene in enamel and dental caries in children

LIU Qiong,QIAN Hong   

  1. Department of Pediatric Dentistry, Stomatological Hospital,Southern Medical University,Guangzhou,Guangdong 510260,China
  • Received:2018-01-08 Online:2018-08-10 Published:2018-08-10
  • Contact: QIAN Hong,


刘琼, 钱虹   

  1. 南方医科大学口腔医院儿童口腔科,广东 广州 510260
  • 通讯作者: 钱虹,
  • 作者简介:刘琼(1983-),女,湖南人,主治医师,硕士学位,主要研究方向为儿童口腔医学。
  • 基金资助:
    广东省科技计划项目 (粤科函规财字[2014]807号); 广州市科技计划项目 (1563000340)

Abstract: Caries are the most common disease in children.Dental caries in children are not self-healing, and if the disease develops, they will cause local pain and abscess, thereby resulting in chewing difficulties, sleep difficulties, and even affecting children′s growth.There are many causes of caries:bacteria, unhealthy diets, poor oral hygiene habits and so on.Recently, more and more scholars have found that the occurrence of caries is closely related to the susceptibility of host, and researches mainly focus on the protein in enamel.This article reviews the progress on the correlation of polymorphism of protein gene in enamel with the occurrence of children dental caries.

Key words: children dental caries, gene, enamel protein

摘要: 龋病在儿童中最为常见,由于儿童龋病不会自行修复,且发展下去会引起局部疼痛、脓肿,导致咀嚼困难、睡眠困难,甚至会影响儿童的生长发育。引起龋病的原因有很多:细菌、不健康饮食、不良的口腔卫生习惯等。近年来越来越多的学者发现龋病的发生与宿主的易感性关系密切,研究热点主要为牙釉质中的相关蛋白质。本文就牙釉质中蛋白质基因的多态性和儿童龋病的发生是否具有相关性的研究进展作一综述。

关键词: 儿童龋病, 基因, 牙釉质蛋白

CLC Number: