Abstract: Objective To explore the relationship between children asthma exacerbation and air pollution and meteorological factors in Wenzhou city. Methods The data of hospitalized children with asthma exacerbation were collected in Wenzhou city from July 2013 to June 2014 and the data of the local air pollution and meteorological factors were collected in the same period too.Then the relationship between asthma exacerbation number and air pollution and meteorological factors were analyzed by straight line correlation,multi-variant linear stepwise regression methods. Results Asthma exacerbation number seemed to go up as air pollution got worse.Inhalable particles (pm10) was the major impact index and had the most significant correlation with the number asthma exacerbation children. Conclusions pm10 is an important factor to affect children developing asthma exacerbation in Wenzhou city,especially to cases of simple asthma exacerbation.Environmental protection should be done well to reduce the incidence of asthma exacerbation in children.

Key words: asthma, air pollutant, inhalable particles, children

摘要： 目的 探讨温州儿童哮喘发作与空气污染及气象因子的相关性,为预防儿童哮喘发作提供理论依据。方法 收集2013年7月-2014年6月因哮喘发作在本科室住院治疗的患儿资料,以及同时期温州空气主要污染物浓度和气象因子数据资料,通过双变量相关性分析法、多元线性逐步回归分析法分析各月哮喘发作住院的患儿例数与各项空气污染物浓度及各气象因子的相关性。结果 哮喘发作住院的患儿例数随空气污染物浓度升高呈增加趋势,其中可吸入颗粒物(pm10)浓度与哮喘住院患儿例数(尤其单纯哮喘例数)关系密切,呈显著正相关(P=0.039,r=0.601;P=0.020,r=0.660)。结论 空气中pm10浓度升高能诱发儿童哮喘发作,尤其增加儿童单纯哮喘发作的发病率。故做好环境保护,降低空气污染,对减少儿童哮喘发作有重要意义。

关键词: 哮喘, 空气污染物, 可吸入颗粒物, 儿童