Abstract: Objective To assess the auditory/visual attention and response control ability of children with congenital hypothyroidism (CH) compared to healthy controls (HC). Methods 36 children with CH,aged (8.64±2.51) years,44.4% males,were compared with HC.Clinical data were collected from medical charts and questionnaires seeking information on family history,birth and perinatal period events,medications,and overall health history.All children were administrated by visual and auditory continuous performance test(IVA-CPT).The results were analyzed by statistic. Results The children with CH group had lower scores than control group (P<0.01) in auditory attention quotient,visual attention quotient and full attention quotient.In the aspect of control response,two groups of children in the auditory control and comprehensive control of comparative difference were not statistically significant,but quotient,differences between the two groups of children had statistical difference relatively in the visual control. Conclusion The children with CH performed more poorly than controls in sustained attention,especially the visual attention.

Key words: congenital hypothyroidism, visual and anditory continuous performance test, child

摘要： 目的 对比先天性甲状腺功能减低症(congenital hypothyroidism,CH)学龄期儿童与正常儿童的视听整合持续测试表现特征,探讨患儿反应控制力及持续性注意力损害特点,为进一步提高治疗效果提供理论依据。方法 运用视听整合持续操作测试对36例CH儿童[男童16例,女童20例,年龄6～12.9岁,平均年龄(8.64±2.51)岁]和与之匹配的36名正常儿童进行测试,对其测试结果进行比较分析。结果 两组儿童在听觉注意力、视觉注意力以及综合注意力商数上的差距具有统计学意义,病例组儿童较正常组儿童得分低。在反应控制力方面,两组儿童在听觉控制力和综合控制力比较上差异不具有统计学意义,而在视觉控制力上的比较,两组儿童的差异具有统计学差异。结论 CH学龄期儿童在持续注意力上存在缺陷,以视觉注意力缺陷为主要表现,对CH儿童的治疗目标需包括提高持续注意力方面。

关键词: 先天性甲状腺功能减低症, 视听整合持续操作测试, 儿童