Abstract: Objective To provide reference for the clinical diagnosis and analysis of neonatal seizure. Methods 60 cases of neonatal seizure were totally summarized and the general states,clinical manifestations,modes on set and video electroencephalograms were analyzed. Results The most common causes of neonatal seizure in 60 cases were neonatal hypoxic ischemic encephalopathy(33.3%),infection(13.3%),hypoglycemia(10.0%),intracranial hemorrhage(8.3%) and electrolyte disturbances(8.3%).The most common mode of onset were minimal seizure(41.7%),then clonic seizure(29.1%).The results of 28 (46.7%)cases of video electroencephalogram were normal,and 32 were abnormal,about 53.3%. Conclusions Neonatal seizure are caused by many types of disease.In clinical work,careful observation and necessary examinations,such as video electroencephalogram,are useful to diagnosis and pathogenesis.So better improvements and decrease of sequela of nervous system could be obtained.

Key words: neonatal seizure, pathogenesis, mode of onset, video electroencephalogram

摘要： 目的 对惊厥新生儿临床特点和视频脑电图进行分析,为临床工作中新生儿惊厥的诊断及分析提供参考。方法 总结60例住院新生儿惊厥病例,分析其一般情况、临床表现、常见病因、发作形式及脑电图结果。结果 60例惊厥新生儿中常见病因分别为缺氧缺血性脑病(33.3%)、感染(13.3%)、低血糖(10.0%)、颅内出血(8.3%)及电解质紊乱(8.3%)。发作形式最常见的是微小发作(41.7%),其次是阵挛发作(29.1%)。视频脑电图结果正常为28例(46.7%),异常32例(53.3%)。结论 新生儿惊厥多由原发病引起,临床需注意观察,及时完善视频脑电图等检查,及时找到病因,以便尽早进行干预,有助于改善预后,减少神经系统后遗症。

关键词: 新生儿惊厥, 病因, 发作形式, 视频脑电图