Abstract: AIM: To observe the clinical efficacy and safety of xuesetong pill in the treatment of patients with stroke.METHODS: Xuesetong pill was observed in the paralleled-control, double-blind, and double-simulated clinical trail.RESULTS: Xuesetong pill significantly improved the symptom of patient with stroke. Its total effective rate to the symptom was up to 90. 3 %.After the treatment of xuesetong pill for 2, 3, and 4 weeks, the improvement of traditional medicine symptom, total score of traditional medicine symptom, stroke and total score of stroke were superior to those in the control group (P<0. 05).Its latent period of efficacy was 13. 16±4. 90 days, which was obviously superior to that in the control group (19. 10±6. 78 days)(P<0. 01).No serious side effect was found in the two groups.CONCLUSION: Xuesetong pill has a characteristic of safe, effective, and fast in the treatment of patients with stroke.

Key words: xuesetong pill, stroke, adverse drug effects, clinical trials