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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2006, Vol. 11 ›› Issue (11): 1305-1308.

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Analysis of factors affecting on adverse drug reactions in 122 cases

ZHAN San-hua, YUAN Kong-xian, LI Guo-zhong   

  1. Department of Pharmacy , the People' s Hospital of Tongling City , Tongling 244000, Anhui , China
  • Received:2006-10-15 Revised:2006-11-05 Online:2006-11-26 Published:2020-11-06

Abstract: AIM:To analyze factors affecting on adverse drug reactions ( ADRs) in 122 cases, in order to avoid and reduce occurrence of ADRs.METHODS: The cases of ADRs by the pharmacist and the clinical reports were collected, and then counted uPand analyzed.RESULTS: In 122 cases of ADRs, there were 11 severe cases, the others are ordinary.The most common clinical displays of ADRs were the lesion of skin and the append ants ( 50.82 %) , followed by the lesion of digestive system( 20.49 %) and nervous system responses( 18.03 %).Anti-infective drugs showed the highest proportion of ADRs, accounting for 61.48 % of the total.The affected patients ranged in age over 50 years( 34.42 %) and low age ( 21.32 %).The most of ADRs were induced by IV droP( 91.96 %).CONLUSION:For the child and the old man crowd clinical doctors must be prudent with the medicine, avoiding the unreasonable combination of the medications, use the anti-infective drugs reasonably and strengthen monitoring of its use, in order to reduce occurrence of ADRs.

Key words: drug, adverse reaction, analysis

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