Abstract: AIM: To explore the effect of liquorice on airway inflammation and Th₁/Th₂ imbalance in chronic asthma.METHODS: The chronic asthma model was es-tablished by intraperitoneal ovalbumin.The effect of liquorice on mice model of chronic bronchial asthma was observed, and the levels of serum IFN-γand IL-4 were tested by ELISA.RESULTS: Decreasing inflammatary cells infiltration in pulmonary tissue slices of tiny bronchi-al wall together with increasing serum IFN-γand decreas-ing serum IL-4 levels.CONCLUSION: Liquorice can adjust Th₁/Th₂ imbalance and inhibit the airway inflam-mation.

Key words: liquorice, bronchial asthma, mice mod-el, Th₁/Th₂ imbalance