Abstract: AIM: To observe the effects and safety of intravenous butorphanol tartrate combined with propofol for aponia colonofiberscope operation. METHODS: One hundred and six patients underwenting aponia colonofiberscope operation were divided into two groups randomly, group A (fentanyl combined with propofol) and group B (butorphanol tartrate combined with propofol), and the anesthetized effects of two groups were observed.The vital sign, total dosage of using propofol, analepsia time and the other side effects were compared in two groups.RESULTS: There were no significant difference between group A and group B in BP, HR, the dosage of using propofol and analepsia time, respiratory depression number in group B were less than those in group A.No severe side effect occurred in either groups.CONCLUSION: Butorphanol tartrate combined with propofol using for enteroscope check has good analgesia, mitigate effect, and with less side effect.Especially, respiratory depression effect in group B is better than that in group A.

Key words: butorphanol, propofol, fentanyl, aponiacolonoscopeoperation