Clinical study of sufentanil combined ropivacaine for labor pain in gestational diabetes mellitus

Abstract

Abstract: AIM: To evaluate the effect of sufentanil combined ropivacaine for labor anesthesia on labor outcome and blood glucose during childbirth of gestational diabetes mellitus.METHODS: 125 cases of gestational diabetes mellitus who selected vaginal delivery ,60 cases in study group received sufentanil combined ropivacaine for pain relief during childbirth, 65 cases in control group without any pain relief during childbirth, labor outcome and blood glucose during childbirth were compared between two groups.RESULTS: Patients in study group felt pain relief in ten minutes since receiving CSEA. The duration of active phase in the first stage in study group was significantly longer than that of control group (P＜0.05). Patients who received cesarean section(CS) in study group were lower than that of control group (P<0.05). Blood glucose during childbirth was significantly lower in study group than that of control group (P< 0.05).CONCLUSION: Sufentanil combined ropivacaine could alleviate labor pain,stabilize blood glucose and reduce CS rate during childbirth in GDM patients.

Key words: Sufentanil, Ropivacaine, Labor anesthesia, Gestational diabetes mellitus, Labor outcome, Blood glucose

CLC Number:

R614

WU Ling-ling, FAN Jian-hui, YIN Yu-zhu, WANG Lin-lin, ZHU Juan, HOU Hong-ying. Clinical study of sufentanil combined ropivacaine for labor pain in gestational diabetes mellitus[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2010, 15(8): 920-923.

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