Application of metabonomics in liver and kidney injury research

Abstract

Abstract: Metabonomics is a new developing “omics” in recent years, which has become one of the most active research areas in biomedical field. Due to its promising applications in many fields, metabonomics has been becoming an important component of system biology. Liver injury and kidney injury are common clinical diseases that endanger human health. However, current indicators are lacking of specificity and sensitivity, so that it is difficult to make accurate, timely warning and monitoring. Metabonomics will contribute to comprehensive analysis of diseases from the perspective of metabolic, distinguishing severity of the disease fast and safely, with the result that there can be seen an increasing advantages for the research on the early diagnosis of liver and kidney injury. This paper mainly reviewed the recent application process of metabonomics in liver and kidney injury research.

Key words: Metabonomics, Liver injury, Kidney injury, Recent development

CLC Number:

R969.1

HE Mu, YAO Wei-feng, CAI Xiu-jiang, DING An-wei, JIANG Ye-juan. Application of metabonomics in liver and kidney injury research[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2012, 17(8): 924-930.

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