Pathogenesis, clinical diagnosis and treatment for CKD-MBD

Abstract

Abstract: The abnormal levels of calcium, phosphorus, parathyroid hormone, vitamin D, fibroblast growth factor-23 in the blood of patients with chronic kidney disease (CKD) will not only cause long-term systematic complications, but also lead to bone mineral metabolism imbalance and bone injury, and finally increase the risk of morbidity and mortality with CKD-MBD. In this review, we summarize the pathogenesis, clinical diagnosis and treatment strategy for CKD-MBD.

Key words: chronic kidney disease, bone metabolism, mineral, secondary hyperparathyroidism, vitamin D

CLC Number:

R692

PAN Hai, LIU Jin-xin, ZHANG Yan. Pathogenesis, clinical diagnosis and treatment for CKD-MBD[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2014, 19(6): 695-700.

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