Research progress on the pharmacokinetic profile of borneol

Abstract

Abstract: In recent years, the research for their own properties of borneol and its impact on the rest of the drug in vivo is more. Therefore, it is necessary to summarize the research of borneol in recent years. This paper reviews the progress of borneol and promote other drug on absorption, distribution, metabolism and excretion of pharmacokinetic aspects. The results showed that the borneol can change the blood brain barrier (BBB) ,cornea, skin and other mucous membrane structure, and to promote other drugs through these structures to reach the site of action. But the study of metabolism of borneol is still inadequate,in synthetic borneol is vented or prototype components to be converted into camphor discharge are divided on the issue. More serious problem is that a lot of research ignores the composition owing to the different varieties of characteristics of borneol, making it is impossible to refer to each other, and even inconsistencies between the various research results. These problems are to be solved.

Key words: borneol, cornea, blood-brain barrier, nasal mucosa

CLC Number:

R969

TENG Yi, YANG Hai-ling. Research progress on the pharmacokinetic profile of borneol[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2015, 20(4): 469-475.

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