Welcome to Chinese Journal of Clinical Pharmacology and Therapeutics,Today is Chinese

Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2018, Vol. 23 ›› Issue (4): 451-455.doi: 10.12092/j.issn.1009-2501.2018.04.015

Previous Articles     Next Articles

Effects of Bushentongluo recipe combined with thermosensitive moxibustion therapy apparatus on lumbar disc herniation and its influence on inflammatory factors

SHENG Yougen, XU Haibo, XIA Jianhong, FANG Xing   

  1. Jinhua People's Hospital, Department of Acupuncture and Moxibustion, Jinhua 321000,  Zhejiang, China
  • Received:2017-09-18 Revised:2017-11-17 Online:2018-04-26 Published:2018-04-13

Abstract:

AIM: To investigate the effects of Bushentongluo recipe combined with Moxibustion with thermosensitive herbs on lumbar disc herniation and its influence on inflammatory factors.  METHODS: A total of 240 patients with lumbar disc herniation were divided into observation group and control group, 120 cases in each group. The control group was treated with thermosensitive moxibustion combined with tetrandrine. The observation group was treated with Bushentongluo recipe on the basis of the control group. The modified JOA spine function score (m-JOA scale) was used to assess the changes in the patient's condition. Visual analogue scale (VAS) was used to assess the patient's pain level. The quality of life was assessed by a health survey brief (SF-36 score). The levels of Creactionprotein, interleukin-1β, tumor necrosis factor-α and interleukin-6 were detected before and after treatment in the two groups.RESULTS:The curative effect of the observation group was better than that of the control group. The difference was statistically significant (P<0.05). The m-JOA scores and VAS scores of the two groups were significantly lower than those before treatment, and the SF-36 score was significantly higher than those before treatment (P<0.05). After treatment, the m-JOA score and VAS score of the observation group were significantly lower than that of the control group, and the SF-36 score was significantly higher than that of the control group. The difference was statistically significant (P<0.05). The levels of CRP, IL-1β, TNF-α and IL-6 in the two groups were significantly lower than those before treatment (P<0.05). After treatment, the CRP, IL-1β, TNF-α and IL-6 levels of the observation group were significantly lower than those of the control group. The difference was statistically significant (P<0.05). CONCLUSION: Bushentongluo recipe combined with Moxibustion with thermosensitive drugs is effective in treating lumbar disc herniation and can significantly reduce the inflammatory response.

Key words: Bushentongluo recipe, thermosensitive moxibustion, lumbar disc herniation, inflammatory

CLC Number: