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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2020, Vol. 25 ›› Issue (12): 1436-1440.doi: 10.12092/j.issn.1009-2501.2020.12.017

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Research status of influence of hemodilution on anesthetics and depth of anesthesia

YIN Lei, GUO Jianrong   

  1. Department of Anesthesiology, Shanghai Gongli Hospital, the Naval Military Medical University, Shanghai 200135, China
  • Received:2020-07-24 Revised:2020-09-20 Online:2020-12-26 Published:2021-01-04

Abstract: Perioperative autotransfusion and blood protection has become a hot issue in modern medicine. Hemodilution, as an effective method of saving blood, has been widely used in clinical practice. It can reduce the clinical demand for allogeneic blood source and relieve the tension of clinical blood use to a certain extent. However, hemodilution itself will also have a certain impact on human physiological functions; especially it can affect the pharmacokinetics and pharmacodynamics of anesthetics and the depth of anesthesia. This paper focuses on the effects of hemodilution on anesthetics and anesthesia depth.

Key words: hemodilution, anesthetics, depth of anesthesia

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