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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2006, Vol. 11 ›› Issue (5): 590-592.

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Prophylactic and therapeutic effects of Mugua Pill on adjuvant-induced arthritis in rats

BING Fei-hong, ZHANG Guo-bin, DENG Cheng-zhi1, SU Yan-qi   

  1. Hubei College of Traditional Chinese Medicine, Wuhan 430061, Hubei, China;
    1Dengchengzhi Chinese Doctors Clinique, Laizhou 261400, Shandong, China
  • Received:2006-01-23 Revised:2006-03-13 Online:2006-05-26 Published:2020-12-09

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Abstract: AIM: To investigate the prophylactic and therapeutic effects of MuGua Pill on Freund' s adjuvant-induced arthritis in rats.METHODS: The rat adjuvant-induced arthritis model was established, and the effect of MuGua Pill in the rats were studied.RESULTS: The medicine aimed at primary prevention could obviously control local inflammation, re-swell on d 8 and another paw swelling.The medicine aimed at the secondary pre-vention could control paw swelling and relieve the inflam-mation on limb and tail.CONCLUSION: MuGua Pill has significant prophylactic and therapeutic effects on ad-juvant-induced arthritis in rats.

Key words: MuGua Pill, adjuvant-induced arthri-tis, anti-inflammation

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