Research progress on interaction between tumor microenvironment and breast cancer cells leading to tumor metastasis

doi:10.12092/j.issn.1009-2501.2022.05.010

Abstract

Abstract: Breast cancer is a malignant tumor with strong invasiveness, strong metastasis and high recurrence rate. Breast cancer cells can be transferred to different tissues in a variety of ways. Breast cancer cells can spread because of the tumor microenvironment created by tumor interaction with surrounding cells. This review examines the role and mechanisms of the tumor microenvironment in breast cancer cell metastasis in recent years, including adipocytes, fibroblasts, neuroendocrine cells, immune and inflammatory cells, blood and lymphatic network, and extracellular matrix, as well as how to treat breast cancer metastasis.

Key words: tumor microenvironment, breast cancer, metastasis, invasion, preventive treatment

CLC Number:

R737.9

SHI Jingbin, XIONG Yang. Research progress on interaction between tumor microenvironment and breast cancer cells leading to tumor metastasis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2022, 27(5): 562-574.

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