Anesthetics, analgesics and cognitive function

doi:10.12092/j.issn.1009-2501.2022.12.006

Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2022, Vol. 27 ›› Issue (12): 1365-1374.doi: 10.12092/j.issn.1009-2501.2022.12.006

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Anesthetics, analgesics and cognitive function

NI Yuanbo1, ZHANG Xin1, LI Yi1, LIU Cunming2

1Nanjing Medical University, Nanjing 210000, Jiangsu, China; 2Department of Anesthesiology and Perioperative Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu, China

Received:2022-09-05 Revised:2022-11-30 Online:2022-12-26 Published:2023-01-13

Abstract

Abstract:

Cognitive dysfunction has become a pivotal factor affecting the quality of life of elderly patients. The existing literatures can not explain the factors causing cognitive decline. Many researchers believe that anesthetics and analgesics may play important roles in cognitive dysfunction. This review will discuss the effects of different anesthetics and analgesics on cognitive function and briefly describe their mechanisms, so as to provide reference for the rational choice of medications in clinical practice.

Key words: cognitive dysfunction, general anesthesia, intravenous anesthetics, opioids, inhaled anesthetics

CLC Number:

R614

NI Yuanbo, ZHANG Xin, LI Yi, LIU Cunming. Anesthetics, analgesics and cognitive function[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2022, 27(12): 1365-1374.

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Anesthetics, analgesics and cognitive function

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