Research progress on antitumor effects of Hedysari radix and active components

doi:10.12092/j.issn.1009-2501.2025.08.013

Abstract

Abstract: Hedysari radix is the characteristic chinese medicine of Gansu Province, with "MiCang Hedysari radix" as the best. Modern pharmacological research has shown that it has polysaccharides and flavonoids, which have good anti-tumor effects and can inhibit the occurrence and development of various cancers, such as lung cancer, liver cancer, and breast cancer. Cancer is ranked as the second leading cause of death in the world, and the morbidity and mortality rates are increasing year by year, seriously affecting the quality of life. At present, with the modernization of Traditional Chinese Medicine (TCM), there has been a significant breakthrough in the treatment of malignant tumors with TCM. Based on this, by collating the relevant literature at home and abroad in recent years, the anti-tumor effects and mechanisms of Hedysari radix and its active ingredients are summarized to provide a scientific basis for the study of elucidating the material basis of the anti-tumor effects of Hedysari radix and to promote the development of the Hedysari radix industry.

Key words: Hedysari radix, active ingredients, anti-tumor, mechanism of action

CLC Number:

R73
R932

WEI Xiaocheng, LI Xinrong, HE Jungang, LI Xu, QIANG Zhengze, WANG Yan, WANG Mingwei, LI Chengyi. Research progress on antitumor effects of Hedysari radix and active components[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2025, 30(8): 1112-1121.

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