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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2013, Vol. 18 ›› Issue (6): 715-720.

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Molecular targeted therapy of colorectal cancer

SHENG Li-li, JI Zhao-ning   

  1. Yijishan Hospital of Wannan Medical College, Wuhu 241000, Anhui, China
  • Received:2012-09-18 Revised:2013-01-07 Published:2013-06-19

Abstract: Colorectal cancer is one of the most common malignant tumors. For patients with metastatic colorectal cancer (mCRC), chemotherapy with fluoropyrimidines, oxaliplatin and irinotecan is the main treatment, but multi-drug resistance occurs very often. In recent years the successful development of targeted therapy improves survival in patients with mCRC. This article reviews the development of targeted agents for the treatment of mCRC.

Key words: Colorectal cancer, Targeted therapy, Bevacizumab, Cetuximab, Panitumumab

CLC Number: