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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2014, Vol. 19 ›› Issue (6): 695-700.

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Pathogenesis, clinical diagnosis and treatment for CKD-MBD

PAN Hai, LIU Jin-xin, ZHANG Yan   

  1. Center for System Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai 200093, China
  • Received:2013-12-27 Revised:2014-06-05 Published:2014-07-01

Abstract: The abnormal levels of calcium, phosphorus, parathyroid hormone, vitamin D, fibroblast growth factor-23 in the blood of patients with chronic kidney disease (CKD) will not only cause long-term systematic complications, but also lead to bone mineral metabolism imbalance and bone injury, and finally increase the risk of morbidity and mortality with CKD-MBD. In this review, we summarize the pathogenesis, clinical diagnosis and treatment strategy for CKD-MBD.

Key words: chronic kidney disease, bone metabolism, mineral, secondary hyperparathyroidism, vitamin D

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