Abstract: Objective To investigate the levels and deficience of 25-hydroxyvitamin D [25-(OH)D]in children at 3～6 years old. Methods Two kindergarten which have more than 200 children in each district were chosen,in total of ten kindergarten.a survey about vitamin D was conducted,the parents informed choice on the basis of the investigation.All tests were done in April to June 2013. Results A total of 753 cases of 3 ~ 6 years old children in the detection of vitamin D,183 cases (24.3%) were relative sufficient,360 cases (47.8%) were relative deficient;207 cases (27.5%) were absolutely deficient.There were statistical differences between different age groups in the deficience of vitamin D(P＜0.05)There Was no statistical difference between different gender groups(P>0.05).In these children,only 11.6% of the children drank milk more than 500ml every day,75.8% of the children didn't take any calcium and cod liver oil for more than one month,33.5% of the children's activity time was up to 1 hour after school. Conclusion The deficiency rate of 25-(OH)D might be high in children of 3～6 years old in Chengdu,we need to do something to improve the level of vitamin D.

Key words: vitamin D deficiency, 25-hydroxyvitamin D, child

摘要： 目的 了解成都市3～6岁儿童25-羟维生素D[25-(OH)D]水平及缺乏率,为儿童维生素D缺乏症的防治提供依据。方法 成都市每个区选择2所在园儿童数在200人以上幼儿园共10所,先发放调查问卷进行基础调查,在家长知情选择的基础上进行维生素D的检测。所有检测在2013年4～6月间完成。结果 共有753例3～6岁儿童进行的维生素D的检测,血清25-(OH)D适宜水平183例,占24.3%,不足360例,占47.8%,缺乏207例,占27.5%。不同年龄维生素D缺乏发生率比较差异有统计学意义(P＜0.05),不同性别组25-(OH)D水平差异无统计学意义(P＞0.05)。753名儿童中 ,每天喝牛奶达到500mL的只占到11.6%, 75.8%的儿童近一个月内未服用任何钙及鱼肝油制剂;有33.5%儿童放学回家后户外活动时间达1 h。结论 成都市3～6岁儿童25-(OH)D缺乏率较高,需要采取措施提高维生素D水平。

关键词: 维生素D缺乏, 25-羟维生素D, 儿童