Abstract: Objective To understand the epidemiological characteristics and epidemic trend of pertussis in Hubei province in 2005-2015,and provide scientific basis for the strategy of monitoring and controlling pertussis. Method The individual data of pertussis cases from National Notifiable Disease Reporting System in Hubei during January 1^st 2005 to December 31^st 2015 were analyzed descriptively. Results Totally 565 cases were reported in Hubei in 2005-2015,with no cases died.The reported incidence of pertussis declined from 0.163 to 0.047 cases per 100 000 in 2005-2009,keep a low level from 0.028 to 0.056 cases per 100 000 in 2010-2013,showed a noticeable rising trend in 2014,and reached 0.217 cases per 100 000 in 2015.The disease occurred all through the year and peaked in March to September,which accounted for 83.4% of the total cases that mainly occurring in infants,around 62.7% cases were less than 1 year old.A proportion of 85.5% of the cases were scattered children. Conclusions Laboratory diagnosis Methods of pertussis should be improved.The proportion of pertussis cases diagnosed by laboratory should be increased,and the incidence should be estimated by active surveillance to effectively control and prevent prevalence of pertussis with reinforce of full-course immunization.

Key words: pertussis, epidemiological characteristic, incidence

摘要： 目的 了解湖北省2005-2015年百日咳的流行特征及近年来湖北省百日咳的流行趋势,为预防控制百日咳提供科学依据。方法 运用流行病学描述性分析方法对国家疾病监测信息报告管理系统报的百日咳病例数据进行分析。结果 2005-2015年湖北省共报告百日咳病例565例,无死亡病例。2005-2009年报告发病率从0.163/10⁵降至0.047/10⁵,2010-2013年维持在较低水平,发病率处于0.028/10⁵~0.056/10⁵,2014年开始上升,至2015年发病率为0.217/10⁵。全年均有发病,主要发病高峰在3~9月份,占病例总数的83.4%,病例主要集中在婴幼儿,62.7%的病例集中在1岁以下儿童,以散居儿童为主(85.5%)。结论 应完善实验室诊断方法,提高百日咳病例的实验室诊断比例,并通过主动监测估计发病率,加强全程免疫,以有效防控百日咳的感染和流行。

关键词: 百日咳, 流行特征, 发病率