journal1 ›› 2019, Vol. 27 ›› Issue (8): 847-850.DOI: 10.11852/zgetbjzz2018-1529

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Research progress on the influence of maternal vitamin D deficiency on the neurobehavioral development of offspring

ZHANG Ying-kuan, YANG Shu-fen   

  1. Department of Pediatrics,the Second Affiliated Hospital of Harbin Medical University,Harbin,    Heilongjiang 150086,China
  • Received:2018-10-26 Online:2019-08-10 Published:2019-08-10
  • Contact: YANG Shu-fen,


张颖宽综述, 仰曙芬审校   

  1. 哈尔滨医科大学附属第二医院,黑龙江 哈尔滨 150086
  • 通讯作者: 仰曙芬,
  • 作者简介:黑龙江省社会发展攻关项目(070400020047)

Abstract: Currently vitamin D deficiency is prevalent in the worldwide. And pregnant women are one of the high-risk groups with vitamin D deficiency. Maternal vitamin D deficiency would cause skeletal,immune and endocrine diseases. As a neuroactive steroid hormone,vitamin D has an indispensable effect on the neurobehavioral development of offspring,which has been paid more and more attention to. This review summarizes the effects of maternal vitamin D deficiency on neurobehavioral development in offspring.

Key words: pregnant women, offspring, vitamin D, maternal vitamin D deficiency, neurobehavioral development

摘要: 目前世界范围内维生素D缺乏的患病率相当高,其中孕母是维生素D缺乏的高危人群之一。孕母维生素D缺乏可导致后代骨骼疾病、免疫系统疾病、内分泌系统疾病,有研究发现维生素D作为一种具有神经活性的类固醇激素,对后代神经行为发育具有不可或缺的作用,孕母维生素D缺乏对后代神经行为发育的影响日益受到关注。本文就孕母维生素D缺乏对后代神经行为发育的影响及其机制进行综述。

关键词: 孕母, 后代, 维生素D, 孕母维生素D缺乏, 神经行为发育

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