Research advances on pathogenesis and treatment of sleep disorders for children with cerebral palsy

doi:10.11852/zgetbjzz2020-0248

Abstract

Abstract: Sleep disorders are increasingly prevalent in children.As one of the most common neurological diseases, children with cerebral palsy suffer serious and higher incidences of sleep disorders due to its persistent brain damage and comorbidities.It will seriously affect the growth and development of children with cerebral palsy and the rehabilitation effects.The mechanism of cerebral palsy with sleep disorders is not clear and there is no specific treatment.This review will focus on the epidemiological study, pathogenesis, diagnosis and treatment of sleep disorders in children with cerebral palsy.

Key words: cerebral palsy, sleep disorders, children

摘要： 儿童睡眠障碍发病日益增高,脑性瘫痪作为儿童最常见的神经系统疾病,脑功能受损持续存在且共患病多,脑瘫患儿合并睡眠障碍的比例较普通儿童更高且病情更重,严重影响了生长发育及其康复疗效。脑瘫儿童睡眠障碍的发生机制尚未明确且无特异性治疗方法,本文将重点对脑瘫合并睡眠障碍的流行病学研究、发生机制、诊断评估方法以及治疗研究进展进行综述。

关键词: 脑性瘫痪, 睡眠障碍, 儿童

CLC Number:

R742.3

ZHANG Yue-hua, YU Zhi-hua, KONG Mian. Research advances on pathogenesis and treatment of sleep disorders for children with cerebral palsy[J]. Chinese Journal of Child Health Care, 2021, 29(5): 515-517.

张月华, 余志华, 孔勉. 脑性瘫痪儿童合并睡眠障碍的机制及治疗研究进展[J]. 中国儿童保健杂志, 2021, 29(5): 515-517.

References

[1] 黄学平,袁文茜,王厚融,等.脑瘫患儿睡眠障碍研究进展[J].云南中医中药杂志,2018,39(6):78-81.
[2] 熊妮娜,候嘉训,李媛媛,等.脑瘫患儿睡眠习惯调查[J].中国康复理论与实践,2012,18(7):671-673.
[3] 吴兆芳,姜琨,刘文华,等.脑瘫儿童睡眠障碍及影响因素的Logistic回归分析[J].中国儿童保健杂志,2011,19(1):48-50.
[4] 刘娟,周洪涛,熊裕娟,等.脑性瘫痪儿童睡眠障碍的调查分析[J].临床医学工程,2014,21(12):1652-1653,1656.
[5] 毛英丽,贾飞勇,胡晓兰,等.脑性瘫痪的早期诊断及治疗[J].中国妇幼保健, 2009,24(9):1235-1236.
[6] Linda H, Patricia L, Elise M,et al.A systematic review and meta-analysis of the prevalence of sleep problems in children with cerebral palsy: how do children with cerebral palsy differ from each other and from typically developing children?[J].Sleep Health,2019,5(6):555-571.
[7] Zahra G, Ali HS, Nazila A, et al.Correlation between sleep disorders and function in children with spastic cerebral palsy[J].Iran J Child Neurol,2019,13(3):35-44.
[8] 张琪然,张小遥,黄柳,等.儿童睡眠及睡眠障碍研究的回顾与展望[J].中国临床护理,2018,10(6):461-466.
[9] 麦坚凝.重视儿童期睡眠障碍的诊治[J].中国实用儿科杂志,2010,25(9):657-658.
[10] Iversen PL, Warren TK, Wells JB, et al.Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus andMarburg virus infections[J].Viruses,2012,4(11):2806-2830.
[11] 牛国辉,朱登纳,袁向东,等.注射鼠神经生长因子对痉挛型脑瘫运动功能的改善作用[J].中国实用神经疾病杂志,2019,22(6):591-598.
[12] 王国祥,梁兵,陶蓉,等.基于ICF-CY的脑性瘫痪儿童运动功能评定及水疗方案[J].中国康复理论与实践,2017,23(2):146-150.
[13] 郝文哲,吴卫红.脑瘫儿童呼吸功能特点及水疗的作用[J].中国康复理论与实践, 2008,14(10):948-950.
[14] 粟俊,柴铁劬,李磊.小儿脑瘫睡眠呼吸障碍及异常脑电图的研究[J].中国康复医学杂志,2006,21(2):156-157.
[15] 陈哨军.脑性瘫痪与睡眠呼吸暂停[J].耳鼻咽喉头颈外科, 2003,10(6):375-377. [16] 庄维崧,朱磊,陈亿雯,等.脑性瘫痪患儿消化功能康复的研究进展[J].中国康复理论与实践,2017,23(11):1299-1303.
[17] 徐怡,赵晓科,陈梦莹,等.虚拟现实技术缓解痉挛型脑性瘫痪患儿治疗性疼痛的效果[J].中国康复理论与实践,2019,25(12):1458-1462.
[18] 殷晓荣.神经发育行为障碍儿童的睡眠障碍[J].中国儿童保健杂志,2017,25(10):1030-1033.
[19] 邹品芳,周奇志,蔡定均,等.针刺调节失眠症睡眠结构和中枢神经递质的研究进展[J].中国中医基础医学杂志,2018,24(3):428-430.
[20] 刘国军,黄河清,陈康宁,等.缺血性脑卒中脑干单胺类神经递质的变化与卒中后睡眠障碍的研究[J].重庆医学,2008,37(20):2308-2309,2312.
[21] 何琪,张骞,邰先桃,等.脊柱推拿对脑瘫幼鼠学习记忆的影响及机制研究[J].中医药导报,2018,24(11):36-39,44.
[22] 蔡淑英,刘振寰.针刺治疗新生儿缺氧缺血性脑损伤机制研究进展[J].中医儿科杂志,2017,13(1):76-78.
[23] 李晓捷,杨影,姜志梅,等.脑瘫仔兔黑质纹状体系神经元数量及超微结构研究[J].中华物理医学与康复杂志,2005,27(7):391-394.
[24] 郇赛,王佩佩,杨暖,等.常规康复治疗联合头部低频电刺激对脑瘫患儿单胺类神经递质、NSE、ET-1及脑血流动力学的影响[J].海南医学院学报,2019,25(5):384-387.
[25] 冯围围,张彤.儿童睡眠评估方法研究进展[J].中国儿童保健杂志,2020,28(4):435-437,446.
[26] 张学君,赖淑贵,洪霖,等.脑瘫儿童睡眠障碍的调查与分析[J].福建中医药大学学报,2014,24(5):47-49.
[27] Sadeh A.The role and validity of actigraphy in sleep medicine:an update[J].Sleep Med Rev,2011,15(4):259-267.
[28] 王惠珊.重视儿童睡眠障碍的评估与防治[J].中国儿童保健杂志,2012,20(9):769-772.
[29] 王德玺,张宗平,刘红,等.体动记录仪在睡眠和睡眠障碍监测中的应用[J].生物医学工程学杂志,2014,31(1):210-213.
[30] 韩芳,唐向东,张斌.中国失眠症诊断和治疗指南[J].中华医学杂志,2017,97(24):1844-1856.
[31] 傅燕虹,秦岭,石娟,等.儿童和青少年失眠诊治现状及研究进展[J].中华实用儿科临床杂志,2017,32(8):637-640.
[32] Badin E,Haddad C,Shatkin JP.Insomnia:the sleeping giant of pediatric public health[J].Curr Psychiatry Rep,2016,18(5):47.
[33] 颜华,张惠佳.经颅磁刺激在儿童脑功能障碍中的应用进展[J].中国康复理论与实践,2015,21(9):1049-1054.
[34] 段华林,张彬,汤梦平,等.重复经颅磁刺激对孤独症谱系障碍患儿睡眠障碍的影响[J].当代护士(下旬刊),2012,20(4):111-113.
[35] 叶荣秋,李木全.维生素D对儿童睡眠障碍症状的改善作用[J].世界睡眠医学杂志,2019,6(11):1542-1544.
[36] 吴小芳,陆丽娜,林霞.中药颗粒剂治疗儿童睡眠障碍的效果分析[J].世界睡眠医学杂志,2019,6(5):600-602.