Research progress on the effects of pulmonary microbiota on the lung development of premature infants

doi:10.11852/zgetbjzz2020-0362

Abstract

Abstract: Pulmonary function is not only the most important determinant of the life of premature infants,but also an important factor affecting their long-term prognosis.The microbial communities in the lungs and intestines are complex,and play an important role in the regulation of pulmonary diseases through the intestinal-pulmonary axis.This review summarizes the aspects of the midgut-lung axis and its pathophysiology in respiratory diseases characterized by bronchopulmonary dysplasia of premature infants,and explores the existing and innovative approaches to prevention and treatment.

Key words: microbiota, bronchopuldysplasia, placenta-gut-lung cross-talk, probiotics

摘要： 肺功能不仅是早产儿生命的最重要的决定因素,也是影响其远期预后的重要因素。肺和肠道微生物群落结构复杂,通过肠-肺轴在肺部疾病中起着重要调控作用。本文将对以支气管肺发育不良为主的呼吸系统疾病中早产儿的肠-肺轴及其病理生理学的许多方面,并探讨现有的和创新的预防和治疗方法。

关键词: 微生物群落, 支气管肺发育不良, 胎盘-肠-肺轴, 益生菌

CLC Number:

R174

PENG Qian, QU Shu-qiang. Research progress on the effects of pulmonary microbiota on the lung development of premature infants[J]. journal1, 2021, 29(3): 289-291.

彭倩, 曲书强. 肺微生物群落对早产儿肺发育影响的研究进展[J]. 中国儿童保健杂志, 2021, 29(3): 289-291.

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