Chinese Journal of Child Health Care ›› 2022, Vol. 30 ›› Issue (12): 1336-1340.DOI: 10.11852/zgetbjzz2021-1206

• Review • Previous Articles     Next Articles

Research progress in the application of bacterial lysates in children with respiratory allergic diseases

LI Yu, KAN Xuan   

  1. Department of Pediatrics,General Hospital of Tianjin Medical University, Tianjin 300052,China
  • Received:2021-10-08 Revised:2021-12-06 Online:2022-12-10 Published:2022-11-30
  • Contact: KAN Xuan, E-mail:


李玉, 阚璇   

  1. 天津医科大学总医院儿科,天津 300052
  • 通讯作者: 阚璇,
  • 作者简介:李玉(1994-),女,山西人,在读硕士研究生,主要研究方向为小儿呼吸及消化。

Abstract: The incidence of respiratory allergic diseases in children is increasing year by year, which has become an important disease burden and medical challenge. Bacterial lysates have long been used as an immunomodulator in recurrent respiratory tract infections in children, but have not been studied in depth in allergic diseases. This paper aims to review the progress in the application of bacterial lysates in childhood respiratory allergic disease, so as to provide scientific basis for the application of bacterial lysates in the treatment of allergic rhinitis (AR) and bronchial asthma in children.

Key words: bacterial lysates, allergic rhinitis, bronchial asthma, children

摘要: 儿童呼吸道过敏性疾病的发生率呈逐年升高的趋势,已经成为重要的疾病负担及医疗挑战。细菌溶解产物作为一种免疫调节剂在儿童反复呼吸道感染中的应用由来已久,但在过敏性疾病中的研究还尚未深入,本文旨在综述细菌溶解产物在儿童呼吸道过敏性疾病应用的研究进展,为细菌溶解产物在儿童过敏性鼻炎(AR)及支气管哮喘的应用中提供科学依据。

关键词: 细菌溶解产物, 过敏性鼻炎, 支气管哮喘, 儿童

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