Abstract: Objective To investigate the effect of depth of protein hydrolysate formula milk to children's nutritional status of henoch-schonlein purpura,looking for a balanced diet treating for children. Methods Totally 60 children with allergic purpura visiting the clinic of the pediatric department were consecutively recruited from January 2014 to June 2015.Patients were randomly divided into restricted diet group(30 patients receive traditional restricted diet)and deep hydrolysis group (30 patients receive depth of protein hydrolysate formula milk).30 cases with upper respiratory tract infection who had normal diet were selected as control group in the same period.All children were investigated the dietary per month after diet treating,blood biochemical test,total of 3 times.The differences of food intake,nutritional status were compared between different groups. Results After diet treating three months,the actual intake/recommend of most nutrient was still less than 60% in restricted diet group,total nutrient intake reached 90%~110% in deep hydrolysis group.Serum triglycerides,cholesterol,prealbumin,total protein and albumin levels were higher in deep hydrolysis group compared with restricted diet group,and there was no statistical difference between deep hydrolysis group and control group. Conclusion Depth of protein hydrolysate formula milk can improve nutrients and protein intake of HSP children,is helpful to the healthy growth of children.   

Key words: depth of protein hydrolysate formula milk, allergic purpura, nutritional status, dietary guidance, albumin, prealbumin

摘要： 目的 探讨深度水解蛋白奶粉对过敏性紫癜儿童营养状况的作用和效果,为患儿寻找营养均衡的饮食治疗方法。方法 选取2014年1月-2015年6月在西安交通大学第二附属医院儿科住院治疗的过敏性紫癜患儿60例,随机将患儿分为限制饮食组30例,进食传统限制饮食;深度水解组30例,进食深度水解蛋白奶粉。同期选取在本科治疗的上呼吸道感染患儿30例作为正常对照组,进食正常饮食。于饮食治疗满1、2、3个月时分别给三组患儿进行膳食调查分析及血液生化检验。分析对比三组患儿营养素摄入水平和机体营养状况。结果 饮食治疗3个月后,限制饮食组大部分营养素摄入的实际/推荐百分比仍然低于60%,深度水解组全部营养素摄入的实际/推荐百分比达90%~110%之间,明显高于限制饮食组(P<0.05),与正常对照组相比差异无统计学意义(P>0.05)。深度水解组患儿的血清甘油三脂、胆固醇、前白蛋白、总蛋白和白蛋白水平与限制饮食组相比均明显升高(P<0.05),与正常对照组相比差异无统计学意义(P>0.05)。结论 深度水解蛋白奶粉应用于儿童过敏性紫癜饮食治疗中,提高患儿营养素及蛋白质的摄入水平,改善机体营养状况,利于患儿的健康成长。

关键词: 深度水解蛋白奶粉, 过敏性紫癜, 营养状况, 膳食指导, 血清前白蛋白, 血清白蛋白