Characteristics and treatment progress of cerebral palsy complicated with mental retardaion

doi:10.11852/zgetbjzz2019-0991

Abstract

Abstract: Researches on mental retardation in children with cerebral palsy have raised widespread concerns over the past decade,and have achieved some progress.This review would focus on this aspect.Researches at home and abroad mainly begin with neuroimaging,genetic metabolism,cognitive function,motor function and other aspects.It is found that neuroimaging has certain specificity in mental retardation in children with cerebral palsy,and the level of dyskinesia in children interacts with their level of intelligence.In terms of related treatments,it is generally believed that early intervention is the key to prevention and treatment,while traditional medicine in the motherland plays a unique therapeutic role.

Key words: cerebral palsy, mental retardation, children

摘要： 近十年来脑瘫患儿智力障碍方面的研究已引起普遍关注,并取得一定进展,现就此方面展开综述。国内外研究主要从神经影像学表现、遗传代谢、认知功能、运动功能等几个方面着手调查,发现神经影像学表现在脑瘫患儿智力障碍方面存在一定的特异性,而患儿运动障碍水平与其智力水平互相影响。在相关治疗方面,普遍认为早期干预是防治关键,而祖国传统医学发挥着独特的治疗作用。

关键词: 脑性瘫痪, 智力障碍, 儿童

CLC Number:

R742.3

WANG Ting, LI Xiao-jie, ZHU Qiong, HUANG Yu-zhu. Characteristics and treatment progress of cerebral palsy complicated with mental retardaion[J]. journal1, 2020, 28(7): 756-758.

王婷, 李晓捷, 朱琼, 黄玉柱. 脑性瘫痪并发智力障碍特点及其治疗进展[J]. 中国儿童保健杂志, 2020, 28(7): 756-758.

References

[1] 李晓捷,唐久来,马丙祥,等.中国脑性瘫痪康复指南:第一部分[J].中国康复医学杂志,2015,30(7):749.
[2] 彭桂兰,蔡淑英,黄种钦,等.厦门地区小儿脑瘫临床分型、早期症状及合并症调查分析[J].中国优生与遗传杂志,2016,24(7):128-129.
[3] 王军英,张惠佳,汤清波,等.小儿脑瘫危险因素与合并症相关分析[J].中国病案,2009,12(2):30-31.
[4] Reid SM,Meehan EM,Arnup SJ,et al.Intellectual disability in cerebral palsy:a population-based retrospective study[J].Dev Med Child Neurol,2018,60(7):687-694.
[5] 陈秀洁,姜志梅,史惟,等.中国脑性瘫痪康复指南:第三部分[J].中国康复医学杂志,2015,30(9):972-978.
[6] 姜东文.脑瘫患儿头颅MR与病因、智能发育相关性研究[J].中国医疗器械信息,2017,23(7):65-66,80.
[7] 陈玉萍,吴德,唐久来,等.脑瘫患儿粗大运动与高危因素及头颅MRI表现的相关分析[J].安徽医学,2014,35(1):1-4.
[8] 陈军,刘志翠,侯梅,等.早产脑损伤患儿脑瘫101例的危险因素分析[J].中国儿童保健杂志,2013,21(5):517-520.
[9] Ballester-Plane J,Laporta-Hoyos O,Macaya A,et al.Measuring intellectual ability in cerebral palsy:the comparison of three tests and their neuroimaging correlates[J].Res Dev Disabil,2016,56:83-98.
[10] Bax M,Tydeman C,Flodmark O.Clinical and MRI correlates of cerebral palsy:the European cerebral palsy study[J].JAMA,2006,296(13):1602-1608.
[11] Yoshida S,Faria AV,Oishi K,et al.Anatomical characterization of athetotic and spastic cerebral palsy using an atlas-based analysis[J].J Magn Reson Imaging,2013,38(2):288-298.
[12] Yoshida S,Hayakawa K,Oishi K,et al.Athetotic and spastic cerebral palsy:anatomic characterization based on diffusion-tensor imaging[J].Radiology,2011,260(2):511-520.
[13] Laporta-Hoyos O,Pannek K,Ballester-Plane J,et al.White matter integrity in dyskinetic cerebral palsy:relationship with intelligence quotient and executive function[J].Neuroimage Clin,2017,15:789-800.
[14] Rosa RF,Enk F,Camargo K,et al.Microcephaly-chorioretinopathy syndrom,autosomal recessive form.A case report[J].Sao Paulo Med J,2015,133(4):377-380.
[15] 郝青英,郭新志,吴涛,等.智力低下脑瘫患儿的病因与血清中微量元素关系探讨[J].中国优生与遗传杂志,2000,8(4):109-111.
[16] 王立苹,李晓捷,张虎,等.ApoE基因多态性与脑瘫并发智力落后的关系[J].中国康复,2010,25(4):259-261.
[17] Sigurdardottir S.Intellectual disability in cerebral palsy:a multifaceted epidemiology[J].Dev Med Child Neurol,2018,60(7):640.
[18] Fazzi E,Bova S,Giovenzana A,et al.Cognitive visual dysfunctions in preterm children with periventricular leukomalacia[J].Dev Med Child Neurol,2009,51(12):974-981.
[19] Zhang H,Zhang B,Jia F,et al.The effecs of motor and intellectual functions on the effectiveness of comprehensive rehabilitation in young children with cerebral palsy[J].J Int Med Res,2015,43(1):125-138.
[20] 刘冬芝,尚清,马彩云.不同智力水平对脑瘫患儿康复训练效果的影响[J].医药论坛杂志,2017,38(3):13-14,18.
[21] Michelsen SI,Flachs EM,Damsgaard MT,et al.European study of frequency of participation of adolescents with and without cerebral palsy[J].Eur J Paediatr Neurol,2014,18(3):282-294.
[22] 蔡志军,李巧秀,朱佳宁,等.益脑增智针法联合康复训练治疗脑瘫患儿临床疗效及对精细运动功能和智力发育的影响[J].中国中医药信息杂志,2018,25(12):28-31.
[23] 苗晔,李苗苗,尤登攀.针灸疗法联合智力训练对脑瘫智力障碍患儿智力的影响[J].中医药临床杂志,2018,30(9):1739-1741.
[24] 邢璐璐,张妍.引导式教育护理在脑瘫患儿康复中的应用效果[J].中国当代医药,2018,25(6):173-175.
[25] Piovesana AM,Ross S,Lloyd O,et al.Randomized controlled trial of a web-based multi-modal therapy program for executive functioning in children and adolescents with unilateral cerebral palsy[J].Disabil Rehabil,2016,39(20):2021-2028.
[26] 焦建红.情景互动式模拟训练对脑瘫患儿肢体功能与智力发育的影响[J].临床医学,2018,38(6):36-38.
[27] James S,Ziviani J,King G,et al.Understanding engagement in home-based interactive computer play:perspectives of children with unilateral cerebral palsy and their caregivers[J].Phys Occup Ther Pediatr,2016,36(4):343-358.