Research progress in abnormal birth weight and neurobehavioral development of children and adolescents

doi:10.11852/zgetbjzz2021-1075

Abstract

Abstract: Abnormal birth weight not only affects the physical growth of newborns, but also affects the neurobehavioral development of infants, children and adolescents and even adults.This paper reviews the population-based studies on the effects of abnormal birth weight on neurobehavioral development among children and adolescents from the perspectives of low birth weight infants and macrosomia, finding that low birth weight infants are more prone to cerebral palsy, attention deficit hyperactivity disorder, cognitive impairment and low learning ability in children and adolescents than normal birth weight infants.Macrosomia might increase the risk of abnormal motor function and emotional and behavioral development in children and adolescents.However, the correlation of macrosomia with intelligence quotient (IQ)/cognitive function and academic achievement in children and adolescents varies in related studies.To identify the impact of abnormal birth weight on neurobehavioral development among children and adolescents, it is necessary to further implement a large sample of prospective cohort studies.

Key words: low birth-weight infants, macrosomia, children and adolescents, neurobehavioral development, population-based studies

摘要： 异常出生体重不仅会影响新生儿的体格生长,还会对婴儿期、儿童青少年期甚至成年期的神经行为发育产生影响。本文从低出生体重儿和巨大儿两方面就异常出生体重对儿童青少年神经行为发育影响的人群研究进行综述,结果发现,低出生体重儿比正常出生体重儿在儿童青少年期更易发生脑瘫、注意缺陷多动障碍、认知障碍和学习能力低下等问题。巨大儿会增加儿童青少年的运动功能、情绪行为发育异常的发生风险,但巨大儿与儿童青少年的智商/认知功能和学业成绩间的关联性研究结论尚不一致。要明确异常出生体重对儿童青少年神经行为发育的影响程度,还需进一步开展大样本的前瞻性队列研究。

关键词: 低出生体重儿, 巨大儿, 儿童青少年, 神经行为发育, 人群研究

CLC Number:

R748

LIU Yu, YANG Xin-jun. Research progress in abnormal birth weight and neurobehavioral development of children and adolescents[J]. Chinese Journal of Child Health Care, 2022, 30(7): 759-763.

刘宇, 杨新军. 异常出生体重与儿童青少年神经行为发育的研究进展[J]. 中国儿童保健杂志, 2022, 30(7): 759-763.

References

[1] 谢幸, 孔北华, 段涛.妇产科学[M].9版.北京:人民卫生出版社, 2018.
[2] Thapar A, Cooper M, Rutter M.Neurodevelopmental disorders[J].Lancet Psychiatry, 2017,4(4):339-346.
[3] 梁嬛, 张为远, 李笑天.基于巨大儿发生率的中国孕妇孕期体质量增加的参考范围—多中心横断面研究[J].中华妇产科杂志,2017,52(3):147-152.
[4] Pascal A, Govaert P, Oostra A, et al.Neurodevelopmental outcome in very preterm and very-low-birthweight infants born over the past decade: A meta-analytic review[J].Dev Med Child Neurol, 2018,60(4):342-355.
[5] 陆昶谋, 何梅, 张玲,等.6~11岁儿童行为问题特征分析[J].教育观察, 2019,8(33):3-5.
[6] 沈丽萍, 王杰, 段一凡,等.2000-2016年国内外低出生体重流行趋势[J].卫生研究, 2020,49(5):850-854.
[7] 李冰飞, 朱大伟, 李力.巨大儿的研究进展[J].中国妇产科临床杂志, 2020,21(6):664-666.
[8] Pearson TS, Pons R, Ghaoui R, et al.Genetic mimics of cerebral palsy[J].Mov Disord, 2019,34(5):625-636.
[9] Hafström M, Köllén K, Serenius F, et al.Cerebral palsy in extremely preterm infants[J].Pediatrics, 2018,141(1):e20171433.
[10] Spittle AJ, Dewey D, Nguyen TN,et al.Rates of developmental coordination disorder in children born very preterm[J].J Pediatr, 2021,231:61-67.e2.
[11] Cheong JLY, Anderson PJ, Burnett AC, et al.Changing neurodevelopment at 8 years in children born extremely preterm since the 1990s[J].Pediatrics, 2017,139(6):e20164086.
[12] Guellec I, Lapillonne A, Marret S, et al.Effect of intra-and extrauterine growth on long-term neurologic outcomes of very preterm infants[J].J Pediatr, 2016,175:93-99.e1.
[13] Abolfotouh MA, Al Saif S, Altwaijri WA, et al.Prospective study of early and late outcomes of extremely low birthweight in Central Saudi Arabia[J].BMC Pediatr, 2018,18(1):280.
[14] Sacchi C, Marino C, Nosarti C, et al.Association of intrauterine growth restriction and small for gestational age status with childhood cognitive outcomes: A systematic review and meta-analysis[J].JAMA Pediatr, 2020,174(8):772-781.
[15] Jaekel J, Baumann N, Bartmann P, et al.Mood and anxiety disorders in very preterm/very low-birth weight individuals from 6 to 26 years[J].Child Psychol Psychiatry, 2018,59(1):88-95.
[16] Bolk J, Farooqi A, Hafström M, et al.Developmental coordination disorder and its association with developmental comorbidities at 6.5 years in apparently healthy children born extremely preterm[J].JAMA Pediatr, 2018,172(8):765-774.
[17] Tommiska V, Lano A, Kleemola P, et al.Analysis of neurodevelopmental outcomes of preadolescents born with extremely low weight revealed impairments in multiple developmental domains despite absence of cognitive impairment[J].Health Sci Rep, 2020,3(3):e180.
[18] Yamada T, Akaishi R, Yamada T, et al.Risk of cerebral palsy associated with neonatal encephalopathy in macrosomic neonates[J].Obstet Gynaecol Res, 2014,40(6):1611-1617.
[19] Perenc L, Guzik A, Podgórska-Bednarz J, et al.Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction[J].Sci Rep, 2021,11(1):6349.
[20] Chen R, Tedroff K, Villamor E, et al.Risk of intellectual disability in children born appropriate-for-gestational-age at term or post-term: Impact of birth weight for gestational age and gestational age[J].Eur J Epidemiol, 2020,35(3):273-282.
[21] Lei X, Zhao D, Huang L, et al.Childhood health outcomes in term, large-for-gestational-age babies with different postnatal growth patterns[J].Am J Epidemiol, 2018,187(3):507-514.
[22] Soheilipour F, Shiri S, Ahmadkhaniha HR, et al.Risk factors for attention-deficit/hyperactivity disorder: A case-control study in 5 to 12 years old children[J].Med Pharm Rep, 2020,93(2):175-180.
[23] Van Lieshout RJ, Savoy CD, Ferro MA, et al.Macrosomia and psychiatric risk in adolescence[J].Eur Child Adolesc Psychiatry, 2020,29(11):1537-1545.
[24] Tamai K, Yorifuji T, Takeuchi A, et al.Associations of birth weight for gestational age with child health and neurodevelopment among term infants: A nationwide Japanese population-based study[J].J Pediatr, 2020,5:S0022-3476(20)30829-5.
[25] Yang Y, Qi Y, Cui Y, et al.Emotional and behavioral problems, social competence and risk factors in 6~16-year-old students in Beijing, China[J].PLoS One, 2019,14(10):e0223970.
[26] Frank CE, Speechley KN, Macnab JJ, et al.Infants born large for gestational age and developmental attainment in early childhood[J].Int J Pediatr, 2018,2018:9181497.
[27] Solis-Urra P, Esteban-Cornejo I, Cadenas-Sanchez C, et al.Early life factors, gray matter brain volume and academic performance in overweight/obese children: The ActiveBrains project[J].Neuroimage, 2019,202:116130.
[28] Khambalia AZ, Algert CS, Bowen JR, et al.Long-term outcomes for large for gestational age infants born at term[J].J Paediatr Child Health, 2017,53(9):876-881.