Abstract: Objective To study the efficacy and safety of 3+2 weight loss program and the factors that affect the weight loss. Methods A total of 85 obese children who visited the Second Affiliated Hospital of Xi'an Jiaotong University from July 2011 to January 2013 were used as intervention group; 85 cases of obese children who were extracted from primary and secondary schools in Xi'an area were used as obese control group,and 85 normal weight children used as control by 1∶1 random sampling.Height and body mass index (BMI) in three groups were compared,and the related effluence factors were analyzed. Results After sixth months,BMI of intervention group decreased having statistical significance (P<0.05);The height growth of intervention group was higher than that of others,having statistical significance (P<0.05).In univariate analysis and logistic regression analysis,mother's education levels,more than half an hour of exercise and implement of both exercise and diet program were effective factors of weight loss. Conclusion "3+2" weight loss program,which is safe and feasible,has no influence on the height of 7~18 year-old obese children.

Key words: 3+2 weight loss program, obese, children, efficacy

摘要： 目的 研究3+2减重方案对儿童单纯性肥胖的疗效、安全性,以及影响疗效的因素,探索适合国内肥胖儿童的个体化减重方案。方法 以2011年5月-2013年1月在本院小儿内分泌专科门诊诊断的85例单纯性肥胖儿童作为干预组,同时期在西安市区中小学采用11配对方法抽取的85例单纯性肥胖儿童作为肥胖对照组及85例健康儿童作为正常对照组。对三组儿童体重身高随访、监测,并对影响影响疗效的因素进行统计分析。结果 肥胖干预组6月后体质指数(BMI)较前明显减少,差异有统计学意义;肥胖干预组身高增长高于对照组,差异有统计学意义(P<0.05);母亲的文化程度高、每次运动大于半小时和饮食和运动方案联合执行是有效减重的影响因素。结论 3+2减重方案可有效控制7~18岁肥胖儿童体重增长,是安全、有效可行的个体化减重方案。

关键词: 3+2减重方案, 单纯性肥胖, 儿童, 疗效