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中国临床药理学与治疗学 ›› 2004, Vol. 9 ›› Issue (1): 63-66.

• 研究原著 • 上一篇    下一篇

用晶体混浊分类系统Ⅲ探讨复方水蛭滴眼液防治老年性白内障的临床研究

黄秀榕, 祁明信1, 张松青1, 陈胜1, 柯发杰1, 潘洁1   

  1. 福建中医学院现代医学部,1附属第二人民医院, 福州 350003, 福建
  • 收稿日期:2003-06-13 修回日期:2003-07-12 出版日期:2004-01-26 发布日期:2020-11-16
  • 通讯作者: 黄秀榕,女, 教授, 硕士导师, 研究方向:白内障的临床与基础研究。Tel:0591-3570887 3570171 Fax:3570887 E-mail: qihuang@netease.com
  • 基金资助:
    福建省卫生厅重点项目(NO.W2000601); 福建省科技厅科研基金资助(NO.K97045)

Clinical study of protection and treatment of leech compound eye drops on senile cataract by the lens opacities classification system Ⅲ

HUANG Xiu-Rong, QI Ming-Xin1, ZHANG Song-Qing, CHEN Sheng1, KE Fa-Jie1, PAN Jie1   

  1. Department of Modern Medicine, 1the Second Affiliated Hospital, Fujian College of Traditional Chinese Medicine, Fuzhou 350003, Fujin, China
  • Received:2003-06-13 Revised:2003-07-12 Online:2004-01-26 Published:2020-11-16

摘要: 目的: 用晶体混浊分类系统Ⅲ(lens opacities classification system Ⅲ, LOCS Ⅲ) 探讨复方水蛭(shui zhi, SZ) 滴眼液对老年性白内障的防治作用。方法: 采用以民间验方为基础、以SZ 为主要成分、富含锌和维生素C 的复方SZ 滴眼液, 并以进口抗白内障药物吡诺克辛钠滴眼液(吡诺克辛) 为对照组, 应用LOCS Ⅲ晶体混浊分类系统观察和比较两种滴眼液对老年性白内障的防治作用。结果: 复方SZ 滴眼液组视力提高率(76 %) 、晶体混浊减低率(59 %) 、有效率(66 %) 均明显优于吡诺克辛滴眼液对照组(2.0 %、0 %和2.0 %) 。且无明显的不良反应。结论: 复方SZ 滴眼液是一种安全、有效的抗白内障药物, 疗效优于进口抗白内障药物吡诺克辛滴眼液。

关键词: 老年性白内障, 中药, 水蛭滴眼液, 锌, 临床研究, 维生素C, 晶体混浊分类

Abstract: AIM: To investigate the protection and treatment of compound leech (Co-SZ) eye drops on senile cataract by the lens opacities classification system Ⅲ (LOCS Ⅲ).METHODS: Co-SZ eye drops were compounded by adding composition full of zinc and vitamin C to SZ eye drops.Pirenoxine sodium eye drops of imported agent were set as control.The protection and treatment of two eye drops on senile cataract were observed and compared by LOCS Ⅲ.RESULTS: The improve rate (76 %) of vision, letdown rate (59 %) of lens opacities and efficiency (66 %) in Co-SZ eye drops group were significantly higher than those in pirenoxine sodium eye drops group (2.0 %, 0.0 % and 2.0 %).CONCLUSION: Co-SZ eye drops is a safe and effective anti-cataract agent.

Key words: senile cataract, Chinese medicine, leech, zinc, vitamin C, eye drops, prevention, treatment, lens opacities classification system

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