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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2020, Vol. 25 ›› Issue (9): 1066-1073.doi: 10.12092/j.issn.1009-2501.2020.09.016

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Effects of resveratrol on autophagy of tumor cells

YUAN Lijialong 1, YUAN Ronghui 2, WANG Jin 1, DENG Ziwei 1, WANG Hongqiang 1, DENG Ye 1, GONG Lu 1, JIN Yuanxiang 1, SHI Zhihua 1   

  1. 1 Department of Clinical Pharmacy, Huaihua First People's Hospital, Huaihua 418000, Hunan, China; 2 Huaihua First People's Hospital, Huaihua 418000, Hunan, China
  • Received:2020-05-14 Revised:2020-07-28 Online:2020-09-26 Published:2020-09-30

Abstract: Resveratrol, as a natural autophagy regulator, has good biological activity in anti-tumor. In the anti-tumor process of resveratrol or similar substances, autophagy not only plays an important role in tumor cell apoptosis, proliferation, senescence and metastasis, but also plays a sensitizing effect on clinical radiation therapy and chemotherapy. This paper reviews the role of autophagy in the anti-tumor effect of resveratrol and its research progress.

Key words: autophagy, resveratrol, tumor

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