AIM: To analyze the potential categories and influencing factors of self concealment in breast cancer patients. METHODS: A total of 207 breast cancer patients from two hospitals in Anhui province were conveniently selected and investigated with general information questionnaire, self concealment scale, perceived social support scale and chronic disease stigma scale. Potential profile analysis was used to explore the categories and characteristics of self concealment, and single factor analysis and logistic regression were used to analyze the influencing factors of different categories. RESULTS: Self concealment of breast cancer patients was divided into two categories: low self concealment group and high self concealment group. Logistic regression analysis showed that the main caregivers, comorbidities, perceived social support and sense of shame were the influencing factors of the potential profile of self concealment of breast cancer patients (P<0.05). CONCLUSION: Breast cancer patients have obvious category characteristics. Medical staff should pay attention to the level of self concealment of breast cancer patients, and formulate precision strategies according to different categories of influencing factors.