Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2005, Vol. 10 ›› Issue (4): 371-376.
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WANG Jian-yun, YIN Xiao-xing
Received:
2005-01-31
Revised:
2005-03-16
Online:
2005-04-26
Published:
2020-11-19
CLC Number:
WANG Jian-yun, YIN Xiao-xing. Relationship between transforming growth factor-β1 signal transduction and renal fibrosis of diabetes[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2005, 10(4): 371-376.
1 Lappin DWP, Doran P, GodsonC, Brady HR.Gene respond to hypercaemia[J]. Exp Nephrol, 2002;10:120-9 2 Piek E, Heldin CH, Dijke PT.Specificity, diversity, and regu-lation in TGF-β superfamily signaling[J]. J FASEB, 1999;13: 2105-24 3 Eickelberg O, Centrella M, Reiss M, Kashgarian M, Wells RG.Betaglycan inhibits TGF-β signaling by preventing type Ⅰ -type Ⅱ receptor complex formation[J]. J Biol Chem, 2002; 277:823-9 4 Han DC, Isono M, Hoffman BB, Ziyadeh FN.High glucose stimulates proliferation and type Ⅰ synthesis in renal cortial fi-broblasts:mediation by autocrine activation of TGF-β[J]. J Am Soc Nephrol, 1999;10:1891-9 5 Zhang Y, Musci T, Derynck R.The tumor suppressor Smad4/ DPC4 as a central mediator of Smads function[J]. Curr Biol, 1997;7:270-6 6 Schnaper HW, Hayashida T, HubchakSC, PonceletAC.TGF-β signal transduction and mesangial cell fibrogenesis[J]. Am J Physiol Renal Physiol, 2003;284:F243-52 7 Singh R, Song RH, Alavi N, Pegoraro AA, Singh AK, Leehey DJ.High glucose decrease matrix metalloproteinase-2 activity in rat mesangial cells via transforming growth factor-beta1[J]. Exp Nephrol, 2001;9:249-57 8 于鸿, 王小刚, 陈琦, 张秀荣, 张志刚, 郭幕依.转染 Smad2基因的大鼠系膜细胞 MMP-2 及 TIMP-2 表达的改变[J]. 复旦学报(医学版), 2003;30:549-52 9 Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A. Targed disruption of TGF-β 1 / Smad3 signaling protects against renal tubulointerstitialfibrosis inducedby unilateral ureteral ob-struction[J]. J Clin Invest, 2003;12:1486-94 10 Runyan CE, Schnaper HW, Poncelet AC.Smad3 and PKCδ mediate TGF-β 1 -induced collagen Ⅰ expression in human mesangial cells[J]. Am J Physiol Renal Physiol, 2003;285: F413-22 11 Yang JW, DaiCS, LiuYH.Hepatocyte growthfactor suppress-es renal interstitialmyofibroblast activation and intercepts Smads signal transduction[J]. Am J Pathol, 2003;163:621-32 12 Liu L, Santora R, Rao JN, Guo X, Zhou TT, Zhang HM, et al.Activation of TGF-β-Smads signaling pathway following polyamine depletion in intestinal epithelial cell[J]. Am J Physi-ol, 2003;285:G1056-67 13 Li JH, Zhu HJ, Huang XR, Lai KN, Johnson RJ, Lan HY. Smad7 inhibits fibrotic effect of TGF-β on renal tubular epithe-lial cells by blocking Smad2 activation[J]. J Am Soc Nephrol, 2002;13:1464-72 14 黄云剑, 赵景宏, 张憬, 范晓棠, 张金海, 蔡文琴.Smad6和 Smad7基因治疗对肾小管间质纤维化进程的影响[J]. 中华肾脏病杂志, 2004;20:358-63 15 Yang X, Letterio JJ, Lechleider RJ, Lechleider RJ, Chen L, Hayman R, et al.Targeted disruption of SMAD3 resultsin im-paired mucosal immunity and diminished T cell responsiveness to TGF-β[J]. EMBO J, 1999;18:1280-91 16 Kanasaki K, Koya D, Sugimoto T, Isono M, Kashiwagi A, Haneda M.N-acetyl-seryl-aspartyl -lysyl -proline inhibits TGF-β-mediated plasminogen activator inhibitor-1 expression via inhi-bition of Smads pathway in human mesangial cells[J]. J Am Soc Nephrol, 2003;14:863-72 17 Isono M, CruzMCID, ChenS, Hong SW, Ziyadeh FN.Extra-cellar signal -regulated kinase mediates stimulation of TGF-β 1 andmatrix by high glucose in messangial cells[J]. J Am Soc Nephrol, 2000;11:2222-30 18 Hocevar BA, BrownTL, Hown PH.TGF-β induced fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway[J]. EMSO J, 1999;18:1345-56 19 Hayashida T, Poncelet AC, Hubchak SC, Schnaper HW. TGF-β 1 activatesMAP kinasesinhuman mesangial cells:a pos-sible role in collagen expression[J]. Kedney Int, 1999;56: 1710-20 20 Lee HB, YuMR, Yang YQ, Jiang ZP, Ha H.Reactive oxy-gen species-regulated signaling pathway in diabetic nephropathy [J]. JAm Soc Nephrol, 2003;14:S241-5 21 Gruden G, Zonca S, Hayward A, Thomas S, Maestrini S, Gnudi L, et al.Mechanical stretch-induced fibronectin and transforming growth factor-β 1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent[J]. Di-abetes, 2000;49:655-61 22 Wahab NA, Parker S, Sraer JD, Mason RM.The decorin high glucose responds element andmechanism of its activationin hu-man mesangial cells[J]. J Am Soc Nephrol, 2000;11:1607-19 23 Wang L, Ma R, Flavell RA, Choi ME.Requirement of mito-gen-activated protein kinase kinase 3 (MKK3)for activation of p38αand p38δMAPK isoforms by TGF-β 1 in murine mesangial cells[J]. J Biol Chem, 2002;277:47257-62 24 Yang J, Liu Y.Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis[J]. J Am Soc Nephrol, 2002;13:96-107 25 Hayashida T, Decaestecker M, Schnaper HW.Cross-talk be-tween ERK MAP kinase and Smad signaling pathway enhanced TGF-β-dependent responses in human mesangial cells[J]. J FASEB, 2003;17:1576-8 26 Atfi A, Buisine M, MazarsA, Gespach C.Induction of apop-tosis by DPC4, a transcription factor regulated by transforming growth factor-β through stress-activated protein kinase/ c-Jun N-terminal kinase(SAPK/ JNK)signaling pathway[J]. J Biol Chem, 1997;272:24731-4 27 Yagi K, Goto D, Hamamoto T, Takenoshita S, Kato M, Miya-zono K.Alternatively-spliced variant of Smad2 lacking exton 3: comparisonwith wild-type Smad2 and Smad3[J]. J Biol Chem, 1999;274:703-9 28 Zhang Y, Feng XY, Dernck R.Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription[J]. Nature (London), 1998;394:909-13 29 Abecassis L, Rogier E, Vazquea A, Atfi A, Bourgeade MF. Evidence for a role of MSK1 in transforming growthfactor-β-me-diated responses through p38αand Smad signaling pathway[J]. J Biol Chem, 2004;279:30474-9 30 Sharma K, McGowan TA.TGF-β in diabetic kidney disease: role of novel signaling pathways[J]. Cytokine Growth Factor Rev, 2000;11:115-23 31 Yamane K, Ihn H, Asano Y, JininM, Tamaki K.Antagonis-tic effect of TNF-αon TGF-β signaling through down-regulation of TGF-β receptor type Ⅱin human dermal fibroblasts[J]. J Immunol, 2003;171:3855-62 32 Laping NJ, Grygielko E, Mathur A, Butter S, Bomberger J, Tweed C, et al.Inhibition of transforming growth factor (TGF)-β 1 -induced extracelluar matrix with a novel inhibitor of the TGF-β type Ⅰ receptor kinase activity:SB-43154[J]. Mol Pharmacol, 2002;62:58-64 33 陈建, 何冰, 刘新民, 王海斌, 章魏, 张英.银杏叶制剂治疗肺间质纤维化的实验研究[J]. 中西医结合杂志,2000;20:441-3 |
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