1 Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acety lcholine [ J] . Nature , 1980; 288 : 373-6
2 Palmer RMJ, Ferrige AG ,Moncada S . Nitric oxide release accou- nts for the biological activity of endothelium-derived relaxing · 12 · Chin J Clin Pharmacol Ther 2006 Jan; 11(1)factor[ J] . Nature , 1987; 327 : 524-6
3 J.Rodrigoa Ferna AP, Serranoa J, Peinadob, MA Mart A.The role of free radicals in cerebral hypoxia and ischemia[ J] . Fre Rad Biol Med, 2005; 39 : 26-50
4 Nina J . Solenski MD, Aij-Lie Kwan MD. Attenuation of free radi- cal generation during reversible focal cerebral ischemia with the nitric oxide inhibitor, L-NAME (L-NG-nitro-Larginine methyl ester) [ J] .Brain Research, 2000 ; 862 : 262-5
5 Jiang MH , Omohiro K, Junichi H , Yasumasa H.Different effects of eNOS and nNOS inhibition on transient forebrain ischemia [ J] .Brain Research, 2002 ; 946: 139-47
6 Hobbs A, Higgs A,Moncada S. Inhibition of nitric oxide synthase as potential therapeutic target[ J] .Annu Rev Pharmacol Toxi- col, 1999; 39 : 191 -220
7 Tweel ERW, Nijboer C , Kavelaars A, Heijnen CJ, Groenendaal F, Bel F. Expression of nitric oxide synthase isoforms and nitro- tyrosine formation after hypoxia-ischemia in the neonatal rat brain[ J] . J Neuroimmunol, 2005 ; 167: 64-71
8 Gillardon F, Krep H , Brinker G, Lenz C, Bottiger B, Hoss- mann KA. Introduction of protein inhibitor of neuronal nitric ox- ide synthase cytoplasmic dynein light chain following cerebral ischemia[ J] .Neuroscience , 1998, 84: 81 -8
9 Wiggins AK, Shen PJ, Gundlach AL. Neuronal-NOS adaptor pro- tein expression after spreading depression:implications for NO production and ischemic tolerance[ J] . J Neurochem, 2003; 87 : 1368-80
10 Sun YJ, Jin KL, ChildsJT, Xie L,Mao XO, Greenberg DA. Neu- ronal nitric oxide synthase and ischemia-induced neurogenesis [ J] . J Cereb Blood Flow Metab, 2005; 25 : 485-92
11 Coert BA, Anderson RE, Meyer FB . Is neuroprotective efficacy of nNOS inhibitor 7-NI dependent on ischemic intracellular pH [ J] ? Am J Physiol Heart Circ Physiol, 2003; 284 : 151-9
12 Chu GL, Xin Y, Cheng JB, Shu Y. Expression of neuronal nitric oxide synthase in brain tissue of hypoxic-ischemic neonatal rat and the cerebral protective effect of neuronal nitric oxide syn- thase inhibitor 7-nitroindazole[ J] . Natl Med J China , 2004 ; 84 : 156-8
13 Jang MH , Shin MC, Chang HK, Lee TH, Lee HH , Shin MS , et al . 7-nitroindazole reduces ischemia-induced increment of apop- tosis and cell proliferation in the dentate gyrus of rats[ J] .Neu- rosci Res Commun , 2004; 35 : 164-72
14 姜德华, 金南革 , 玄汉石, 李在硫. 7-NI 减小大鼠暂时性 局灶性脑梗塞灶范围[ J] .中风与神经疾病杂志, 1998;
15 : 342
15 Kahn RA , Panah M , Weinberger J.Modulation of ischemic exci- tatory neurotransmitter and r-aminobutyric acid release during global temporary cerebral ischmia by selective Nnosi[ J] .A nesth A nalg , 1997; 84 : 997
16 Hao J, David K, Zhang LJ, Jarret K, Alba I, Rodriguez, et al . In- hibitors of iNOS protects PC12 cells against the apoptosis in- duced by oxygen and glucose deprivation[ J] .Neurosci Lett, 2005; 375 : 59-63
17 Jafarian-Tehrani M, Louin G, Royo NC, Besson VC, Bohme GA, Plotkine M , et al .1 400 W, a potent selective inducible NOS inhibitor, improves histopathological outcome following traumatic brain injury in rats[ J] .Nitric oxide-biology and chemistry , 2005; 12: 61-9
18 Perez-Asenio FJ, Hurtado O, Burguete MC , Moro MA, Salom JB, Lizasoain I, et al . Inhibition of NOS activity by 1400W de- creases glutamate release and ameliorates stroke outcome after experimental ischemia[ J] .Neurobiol Dis, 2005; 18 : 375-84
19 Pearse DD, Chatzipanteli K, Marcillo AE, Bunge MB , Dietrich WD.Comparison of NOS inhibition by antisense and pharmaco- logical inhibitors after spinal cord injury[ J] .J Neuropathol Exp Neurol , 2003; 62: 1096 -107
20 Jiang H , Koubi D, Zhang L, Kuo J, Rodriguez AI, Hunter TJ, et al . Inhibitors of NOS protects PC12 cells against the apoptosis induced by oxygen and glucose deprivation[ J] .Neurosci Lett, 2005; 375 : 59-63
21 Gokce FM, Bagirici F , Kaplan S, Demir S, Ayyildiz M, Marangoz C . A NOS inhibitor aminoguanidine reduces zinc-induced neuron loss in rat hippocampus[ J] .Neurosci Res Commun, 2003; 33:
53 -62
22 Koreaki S , Costantino I.Effects of aminoguanidine on cerebral ischemia in mice:comparison between mice with and without inducible nitric oxide synthase gene[ J] .Neurosci Lett , 2002; 331 : 25-8
23 Danielisova V, Nemethova M, Burda J . The protective effect of aminoguanidine on cerebral ischemic damage in the rat brain [ J] .Physiol Res, 2004; 53 : 533-40
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