Abstract: AIM: To observe the effects of Yinqu Capsule on blood lipid in rats with experimental hyperlipidemia. METHODS: Rats were fed with fatty forage for two weeks to make the model of hyperlipidemia. The rats were randomly divided into five groups: model group, Xuezhikang group and three dosages of Yinqu Capsule groups. The drugs were administered for two weeks consecutively. The levels of T-CHOL, TG, LDL-C and VLDL-C in serum of rats were detected to observe the preventive and therapeutical effects of Yinqu Capsule. RESULTS: Compared with control group, the levels of T-CHOL, TG, LDL-C, VLDL-C and T-CHOL HDL-C of Yinqu Capsule groups were significantly decreased and the content of HDL-C was slightly increased(P<0.05 or P<0.01). CONCLUSION: Yinqu Capsule could modulate blood lipid of hyperlipidemia rats to a certain extent.

Key words: Yinqu Capsule, hyperlipidemia, rat, blood lipid