Influence of complex prescription traditional Chinese medicine on polycystic ovarian syndrome model rats in glycometabolism

Abstract

Abstract: AIM:To observe the changes of weight, fasting plasma glucose (FPG), insulin (INS) and insulin-like growth factor-1 (IGF-1) of polycystic ovary syndrome (PCOS) model rats, and to explore the influence of complex prescription traditional Chinese medicine on glycometabolism. METHODS:PCOS rat models induced by Poresky method were intervened, and the changes of weight, plasma glucose, and the influence of INS and IGF-1 in serum were observed after treatment. RESULTS:The complex prescription traditional Chinese medicine could decrease the weight, the levels of INS and IGF-1 in serum of PCOS model rats, but the glucose-lowering effect was not significant. CONCLUSION:The complex prescription traditional Chinese medicine can improve the glycometabolism abnormal occurrence of PCOS model rats.

Key words: traditional Chinese medicine, polycystic ovarian syndrome, fasting plasma glucose, insulin, insulin-like growth factor-1

CLC Number:

R589

DEN A-li, XIANG Nan, ZHOU Zhong-ming, JIANG Hui-zhong, ZHANG Ya-bing. Influence of complex prescription traditional Chinese medicine on polycystic ovarian syndrome model rats in glycometabolism[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2009, 14(5): 504-508.

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