Correlation and clinical value of PCT, SVRI, SOFA  in sepsis patients

Abstract

Abstract:

AIM: To discuss the value of the combination of serum procalcitonin concentration (PCT), systemic vascular resistance index (SVRI) and sequential organ failure assessment score (SOFA score) in the early diagnosis of patients with sepsis in the intensive care unit (ICU) ward and clinical application. METHODS: 78 patients with sepsis were divided into the high SVRI group, the normal SVRI group and the low SVRI group on the basis of the SVRI index. The records and tests included the age, the sex, the infection, concentration of serum PCT and SOFA score, cardiac index (CI), central venous pressure (CVP), mean arterial pressure (MAP), global end diastolic volume index (GEDVI) and extravascular lung water index (EVLWI) respectively. The correlations between the records were studied. RESULTS: The records of the age, gender and infection site of each group showed no statistical significance. The SOFA score, serum PCT concentration and cardiac index of low SVRI group were significantly higher than those of the normal SVRI group and the high SVRI group, respectively. There were no statistical significant of the serum PCT concentration, SOFA score and heart index difference of the high SVRI group and the normal SVRI group of patients with sepsis. The spearman analysis showed that SVRI was negatively correlated with the concentration of PCT (r=-6.38,P=0.000), and SOFA score (r=-0.527,P=0.000), respectively. It showed no significant correlation with CI (r=-0.375,P=0.000). The pearson analysis showed that PCT concentration was positively correlated with SOFA score (r=0.69,P=0.000). CONCLUSION: PCT concentration, SVRI, SOFA score were important clinical indexes in assessing the patient's condition and make the plan for that. This method is referential for clinical application.

Key words: sepsis, procalcitonin, system vascular resistance index, SOFA score

CLC Number:

R969

WANG Jian，ZHANG Wen. Correlation and clinical value of PCT, SVRI, SOFA in sepsis patients[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2017, 22(4): 443-447.

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Correlation and clinical value of PCT, SVRI, SOFA in sepsis patients

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