Diabetic erectile dysfunction is a common complication of diabetes that severely affects the quality of life of men and their sexual partners. Active participation in scientific research on diabetic erectile dysfunction is particularly important, and animal models are an important basis for exploring the pathogenesis of the disease, evaluating the efficacy of drug treatments, and developing new drugs. The pathogenesis of diabetic erectile dysfunction is complex, and current treatments mainly focus on regulating blood sugar, anti-oxidative stress, PDE5 inhibitors, stem cell therapy, inhibiting neurovascular injury, anti-fibrosis, traditional Chinese medicine, and other aspects. In particular, correcting hyperglycemia is crucial for preventing or stopping the progression of the disease. This article summarizes and updates existing treatment methods by reviewing the latest literature, and reviews the animal models used in different treatment methods, in order to provide a reference for animal experiments and clinical treatment.