Abstract: Aim Pow deredinjections of luo tai consist of total saponins of panax notoginseng(PNS) which protect againstischemia injury from my ocardial reperfusion injury.Methods ISO-induced acute my ocardial ischemia model in rat was made, which decreased S-T sigments in ECG.Luotai after intravenous injection ororal can protect against S-T sigmentsignificantreduction and ΣS T after ISO induced acute my ocardial ischemia.Results Luotai 50 mg·kg^-1 and 100 mg·kg^-1 significantly inhibited S-T sigment decreases.Conclusion Luo tai protect ISO induced acute my ocardial ischemia and has dose-dependent Effect.T his ISO-induced acute my ocardial ischemia model in rat has somesignificant advantages, forexample, higher stability, good duplication, quickly filtrates, easily masters.

Key words: powdered injections of luotai(consist of PNS), isoproterenol(ISO), rat, myocardial ischemia, electrocardiogram