Abstract: AIM: To evaluate the surface anesthetic effects of compound lidocaine cream-coated endotracheal tube for pediatric abdominal surgery extubation security. METHODS: Sixty 5-12 years old children undergoing abdominal operation under general anesthesia received insertion of the endotracheal tube coated with either compound lidocaine cream(experimental group) or nothing(control group).Pulse Oxygen Saturation (SpO₂),heart rate(HR) and the respiratory end of carbon dioxide(P_ETCO₂)were measured during intubation and extubation.Postoperative pediatric endotracheal tube tolerance and respiratory reaction after anesthesia was recorded.RESULTS:After the two groups of children in the anesthetic effect disappear,compared with the control group,experimental group can be better tolerated endotracheal tube,stable vital signs;the next day,the hoarseness and delirium incidence in experimental group were significantly lower,there was statistically significant difference (P<0.05) .CONCLUSION: Compound lidocaine cream-coated endotracheal tube can inhibit the stress response of the endotracheal tube extubation,with lower postoperative hoarseness and delirium ,can improve the safety of anesthesia extubation in children undergoing abdominal operation under general anesthesia.

Key words: compound lidocaine cream, endotracheal tube, pediatric, abdomen, general anesthesia