Abstract: Objective To explore the developmental profile of children with autism spectrum disorder (ASD) on PEP-3. Methods A total of 52 children with ASD who were divided into two groups according their intelligence level, low-function autism (LFA) and high-functioning autism (HFA), and 26 aged-matched typically children were evaluated by PEP-3 (each group included 23 boys and 3 girls, aged 2~5 years old). Results LFA children exhibited a greater developmental delay in all subtests on PEP-3 as compared with typically children (P<0.001).The scores and developmental ages on the cognitive verbal/preverbal (CVP) and gross motor (GM) subtests were lower in HFA group than TD group (P<0.05).LFA group significantly scored lower than HFA group on CVP, expressive language (EL), receptive language (RL), fine motor (FM) and visual motor imitation (VMI) subtests (P<0.05).For the communication composite and motor composite, children with LFA exhibited "low-high" trend (51.68±14.34 VSs 75.08±9.00, P<0.001), while HFA group presented "balanced" phenomenon (91.40±12.93 VS 87.02±11.66, P=0.205). Conclusion Children with ASD of different intelligence level exhibites differently on PEP-3.

Key words: aautism spectrum disorders, PEP-3, developmental profile

摘要： 目的 探索不同认知功能孤独症谱系障碍(autism spectrum disorder, ASD)儿童在心理教育评估量表第3版(PEP-3)中反应特征, 为临床诊断和康复提供可循依据。方法 以智力测试结果为界定标准, 选择低功能ASD(LFA)、高功能ASD(HFA)和正常对照组儿童各26例, 各组性别、年龄相匹配各组男23例、女3例, 年龄在2~5岁间, 平均年龄分别为(40.92±9.60)、(40.07±7.60)、(40.12±9.31)月, 采用香港版PEP-3量表的功能发展量表对其进行测评分析。结果 LFA儿童在PEP-3所有功能领域的原积分和发展年龄均明显落后于对照组(P<0.001), HFA组的认知、大肌肉测验的原积分和发展年龄均低于对照组(P<0.05);LFA组的认知、语言表达、语言理解、模仿测验的原积分和发展年龄均明显低于HFA组(P<0.001), 小肌肉测验的原积分和发展年龄均低于HFA组(P<0.05)。LFA组在合成项沟通和体能的功能商数表现为“低-高”趋势(51.68±14.34 VS 75.08±9.00, P<0.001), HFA组则呈现“均衡”现象(91.40±12.93 VS 87.02±11.66, P=0.205)。结论 不同认知功能ASD儿童PEP-3评价结果反映了不同模式, 可作为辅助诊断和教育干预的参考。

关键词: 孤独症谱系障碍, PEP-3, 反应模式