Advances in extraction and mechanism of antitumor active components from Fagopyrum dibotrys

doi:10.12092/j.issn.1009-2501.2019.07.018

Abstract

Abstract:

Fagopyrum dibotrys is a medicinal plant of Buckwheat in Polygonaceae collected in Pharmacopoeia. It is widely distributed in the central and southwest of China. The extraction process of its antitumor active ingredients by immersion method is lagging behind. The main antitumor active ingredients, flavonoids and phenols, are concentrated in the rhizome. The main antitumor mechanisms of buckwheat are inhibiting the proliferation and migration of tumor cells, besides, inducing apoptosis and autophagy of cancer cells. In this paper, we reviewed the research progress on the antitumor chemical components, the extraction of active ingredients and the antitumor mechanisms of Fagopyrum dibotrys in order to provide references for further research on antitumor active ingredients and antitumor effects of Fagopyrum dibotrys.

Key words: Fagopyrum dibotrys, antitumor components, extraction of active ingredients, antitumor mechanisms

CLC Number:

R285

LI Hongli, WEN Dandan, ZHOU Meiliang, WANG Haihua, PENG Xixu, GAO Lichen. Advances in extraction and mechanism of antitumor active components from Fagopyrum dibotrys[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2019, 24(7): 833-840.

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