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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2002, Vol. 7 ›› Issue (4): 372-376.

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Inhibitor of apoptosis protein and strategy of tumor therapy

MA Jing, YUAN Shou-Jun   

  1. Department of Pharmacology and Toxicology, Institute of Radiation, Academy of Military Medical Sciences, Beijing 100850
  • Received:2002-05-17 Revised:2002-06-05 Online:2002-08-26 Published:2020-11-24

Abstract: Apoptosis is a cell suicide process with a major role in development and homeostasis in bodies. Dysregulation of apoptosis, involved with inhibitors of apoptosis ( IAPs), contributes a variety of disease states including cancer. The recent progress of members of IAPs family and the anticancer strategy against IAPs is reviewed in this paper.

Key words: inhibitor of apoptosis protein, therapy, tumor

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