Research progress of chitosan derivatives in antitumor studies

Abstract

Abstract: Application of chitosan derivatives in antitumor studies had gained great progress with the development of theory and practice, which exhibited good prospect for its favourable properties, such as stability, biocompatibility, biodegradability, low toxicity and long-term retention in the body.Antitumor properties of chitosan derivatives, application of chitosan derivatives as drug carrier and auxiliary function of physical therapy were concluded in this review.The data showed that chitosan derivatives played an active role in suppression of tumour growth and prolongation of survival period.

Key words: chitosan derivatives, antitumor, carrier

CLC Number:

R969

WANG Xiao-ji, YANG Jing-ya, LIU Jian-wen. Research progress of chitosan derivatives in antitumor studies[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(8): 952-956.

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