Therapeutic effects of Taizhi'an capsules on hyperlipidemia in rats

Abstract

Abstract: AIM: To observe the effects of Taizhi5 an capsules on reducing the hyperlipidemia in rat models, and to explore the mechanisms and the side-effects of Taizhi'an. METHODS: Hyperlipidemia animal models were set up by normal diet and high cholesterol diet in rats. The concentrations of serum lipid were detected by full automatic biochemical instrument. RESULTS: Taizhi'an obviously reduced the concentration of serum total cholesterol, triglycerides (TG) and increased the contents of LPL. Taizhi'an had no obviously influence on the concentration of glutamic oxaloacetic transaminase (GOT). CONCLUSION: Taizhi'an capsule can de-crease the hyperlipidemia. Its mechanism is related to the regulation of lipid metabolism and improvement of the concentration of LPL (lipoprotein lipase).

Key words: Taizhi'an capsule, hyperlipidemia model, LPL, hyperlipidemia, traditional Chinese medicine

CLC Number:

R965.2

WU Nan, ZHANG Qing-Shu, ZHANG Yue-Fei, MAO Yi-Qing, LI Qing-Yi, RUAN Yuan, LING Hu, GAO De-Lul, TAN Huan-Ran. Therapeutic effects of Taizhi'an capsules on hyperlipidemia in rats[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2004, 9(11): 1285-1288.

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Therapeutic effects of Taizhi'an capsules on hyperlipidemia in rats

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