Table of Content

06 May 2012, Volume 20 Issue 5

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Potential roles of miR-152 in nonalcoholic fatty liver disease by the bioinformatic analysis

FENG Yue-ying,LIN Hu,SHI Chun-mei,JI Chen-bo,GUO Xi-rong,FU Jun-fen

2012, 20(5):  391-394. 

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【Objective】 To provide both theoretical and experimental basis for further study of NAFLD via reviewing the previous studies of miR-152 and bioinformatically predicting target genes of miR-152. 【Methods】 All literature of miR-152 was searched in PubMed.The predicted target genes of miRNA-152 were analysed by function enrichment (gene ontology) and signal transduction pathway enrichment (KEGG). 【Results】 miR-152 had been reported in studies of some cancers,preeclampsia and other diseases.The gene ontology analysis showed the predicted target genes of miR-152 were enriched in sensory organ developmentm,cell differentiation,metablism and other biological processes,and the pathway analysis showed the target genes mainly involved in cancers,actin cytoskeleton,adipocytokine,insulin signal and Wnt signaling pathway. 【Conclusions】 There's few study of miR-152 in NAFLD.The predicted target genes of miR-152 are enriched in multiple biological processes,which provid some clues for NAFLD.

Effects evaluation after 6 months Yingyangbao intervention for infants and young children aged 6~24 months in Ningqiang,Shaanxi

LI Li-xiang,CHANG Feng,XU Zeng-kang,WANG Lin-jiang,MAN Qing-qing,FU Ping,ZHANG Jian,SONG Peng-kun

2012, 20(5):  395-397. 

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【Objective】 To evaluate the intervention effects of Yingyangbao on infants and young children aged 6~24 months lived in rural area of Ningqiang,Shaanxi. 【Methods】 All the infants and young children aged 6~24 months in Ningqiang county were fed one sachet Yingyangbao which contains rich high quality protein,various vitamins and minerals per day for 6 months.634 infants and young children were selected as study objects by PPS sampling featured representative characteristics in Ningqiang both at the beginning and at 6 months after it.The length and weight were measured and finger hemoglobin were determined. 【Results】 After 6 months intervention,the average hemoglobin,length,weight,WAZ and WHZ were increased 7.4 g/L,3.3 cm,1.2 kg,0.6 score,0.6 score,respectively,the differences were statistically significant (P<0.01);the prevalence of anemia,stunting,underweight,and wasting was declined 25.1%(P<0.01),1.0%,5.4%(P<0.01),4.0%(P<0.01),respectively by chi-square test. 【Conclusion】 The results indicated that Yingyangbao could decrease the prevalence of anemia,underweight and wasting of these infants and young children aged 6~24 months after 6 months intervention.

Investigation of development and plastic using status of adolescent

CHEN Yao,SHEN Li-xiao,HUANG Hong,LV Ying-bo,LI Feng

2012, 20(5):  398-400. 

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【Objectives】 To learn about the status of physical development,spermatorrhea/menstruation and plastics using habits of junior students and study about the association between physical development and spermarcheal/ menarcheal age.It's the first time to investigate the relationship between plastics using habits and spermarcheal/ menarcheal age. 【Methods】 Body mass index(BMI:kg/m²) was used as the index for physical development.Spermarcheal and menarcheal age were obtained through interview.Plastics using habits were learned through questionnaire.Jonckheere-Terpstra test was used to learn about spermarcheal/menarcheal ages in different physical development status.The relationship between plastic using habits and spermarcheal/menarcheal age was analyzed through simple linear regression. 【Results】 For participants in our investigation,the rate of overweight and obesity was much higher than the rate fo under-weight.At the same time,the rate of overweight and obesity was much higher than that in boys than in girls (P<0.01).A large proportion of the participants had bad habits of using plastics.Spermarcheal age in different physical development status had no statistical significance,while menarcheal age in different physical development status had a statistical significance (P=0.001).There were no significant correlations between plastic using habits scores and spermarcheal age or menarcheal age. 【Conclusions】 Weight control and appropriate use of plastics are especially important for adolescent normal pubertal development.Education of adolescence should be done respectively.

Effect in osteoblasts of infants and toddlers by short-term therapy of three kinds of glucocorticoids

YAN Xue,WU Yu,ZHANG Ya-nan,PI Ya-lei,ZHANG Hui-feng

2012, 20(5):  401-403. 

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【Objective】 To compare the influences in osteoblasts of infants and toddlers by short-term therapy of the three kinds of glucocorticoids (hydrocortisone,methylprednisolone and dexamethasone). 【Methods 】 Thirty children suffered from bronchiolitis were divided into three groups by different kinds of glucocorticoids:the hydrocortisone group,the dosage was 10 mg/(kg·d),the methylprednisolone group,the dosage was 3~5 mg/(kg·d) and the dexamethasone group,the dosage was 0.25~0.5 mg/(kg·d).The courses of treatment were all 5 days.The serum concentrations of bone alkaline phosphatase (BAP)and total alkaline phosphatase (TAP) were measured. 【Results】 1)The serum levels of BAP and TAP in hydrocortisone group and dexamethasone group before and after the treatment were not different significantly(t=0.292,P＞0.05).2)The serum levels of BAP in methylprednisolone group before and after the treatment were (82.15±25.86)U/L and(57.27±17.53)U/L,respectively.There was significant difference(t=3.947,P＜0.01).The serum levels of TAP in methylprednisolone group before and after the treatment were (149.71±22.22) U/L and (117.00±24.93)U/L,respectively.There was significant difference(t=3.111,P＜0.05).3)There was positive correlation both the serum BAP and TAP (R=0.703,P<0.01). 【Conclusions】 The therapy of short-term routine dosage of methylprednisolone could inhibit the function of osteoblasts in infants and toddlers.The serum TAP may replace BAP to monitoring the function of osteoblasts in period of the therapy of glucocorticoids.Under the same clinical effects,hydrocortisone is recommended vis-a-vis methylprednisolone and dexamethasone.

Change of serum concentration of vitamin A and the balance of Th1/Th2 in children with type 1 diabetes mellitus

CHEN Yong-xing,WEI Hai-yan,LI Chun-zhi,ZHANG Ying-xian,WANG Hui-zhen,LIU Xiao-jing,LIU Fang

2012, 20(5):  404-405. 

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【Objective】 To explore change of serum concentrtion of vitamin A,and its influence on the balance of Th1/Th2 in children with type 1 diabetes mellitus. 【Methods】 Totally 32 children with T1DM were taken as T1DM group,and 28 healthy children as control group.The serum level of vitamin A was determined by the method of micro-flourescence,and the levels of IFN-γ and IL-4 in the supernatant were determined by enzyme-linked immunosorbent assay. 【Results】 1)The level of vitamin A in T1DM group was lower than that in control group(P<0.01).2)IFN-γ level produced from PBMC in T1DM group was higher than that in normal control group(P<0.05),IFN-γ/IL-4 ratio was higher than that of normal control group(P<0.01).3)The levels of vitamin A in T1DM group and normal control group both had negative correlation with the levels of IFN-γ produced from PBMC(P<0.05 or <0.01),and negative correlation with the ratio of IFN-γ/IL-4(P<0.05 or <0.01),but had no correlation with the levels of IL-4(P>0.05). 【Conclusions】 The deficiency of vitamin A is present in children with type 1 diabetes mellitus,which is closely correlated with the balance of Th1/Th2.

Reasons and outcome analysis of macrosomia in Qingdao

MA Xiao-hong,WANG Xiu-ying,WANG Cai-xia,WANG Li-min,LUAN Shao-yong,WANG Hai-yan

2012, 20(5):  406-408. 

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【Objective】 To analyze the originated correlation factors of macrosomia as well as its correlation to obesity in Qingdao,to guide duration of pregnancy and offer accordance for monitoring postnatal growth development. 【Methods】 To observe 1 815 cases of macrosomia as observational group,to compare the pregestational BMI,weight gain during pregnancy,body height,'glycometabolism,investigating diet,exercise.The level of leptin,adiponectin,insulin-like growth factor-Ⅰin the cord blood of 80 cases (40 cases macrosomia,40 case normal) were measured by enzyme linked immunosorbent assay(ELISA).BMI were assessed at 6 growth development to monitoring time for macrosomia and AGA. 【Results】 The index of pregestational BMI,weight gain during pregnancy,body height,'glycometabolism in observational group were much more abnormal than those in control group,and the intake of seafood and fruit in diet,the level of leptin,insulin-like growth factor-Ⅰin the cord blood,incidence rate of the overweight by assessing the BMI at postnatal monitoring point were all higher than those in the control group,while the adiponectin and movement time were lower than those in the control group. 【Conclusions】 The pregestational BMI,weight gain during pregnancy,body height,`glycometabolism,diet and exercise of gravida are the reasons to result in macrosomia.Macrosomia has the same pathology fundament as adults obesity,their postnatal incidence rate of overweight raise up obviously.

Impact of pyrethroid pesticides exposure on development of one-year old infants

ZHENG Ming-lan,QI Xiao-juan,WU Chun-hua,WANG Guo-quan,LU Da-sheng,CHANG Xiu-li,ZHOU Zhi-jun

2012, 20(5):  409-412. 

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【Objective 】 To examine associations between pyrethroid pesticides exposure and development in one-year infants. 【Methods】 449 one-year old infants in a county of Jiangsu Province were studied.Their spot urine were collected and pyrethroid pesticides exposure was assessed by measuring pyrethroid metabolites (cis-Cl₂CA,trans-Cl₂CA and 3-PBA).The Physical examination and the DST Scale were done and their relationship with pesticides exposure was evaluated. 【Results】 Pyrethroid metabolites (cis-Cl₂CA,trans-Cl₂CA and 3-PBA) were found among 70.4%,97.6% and 84.2% of these infants,respectively.The weight and the chest circumference among different pyrethroid metabolites levels was significiantly different,but not the body length,the head circumference and the development quotient.The pyrethroid metabolites level was associated with a decrement in weight by using multiple liner analysis. 【Conclusion】 Our findings suggest that exposure to pyrethroid negatively impacts on the weight of one-year infants.

Periods study of nutrition interventions about infants aged 6~24 months in Ningqiang county affected by Wenchuan earthquake

WANG Lin-jiang,XU Zeng-kang,CHANG Feng,FU Ping,ZHANG Jian,ZHANG Tong-jun,ZHANG Han-pei,LI Jian-li,SONG Peng-kun

2012, 20(5):  413-415. 

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【Objective】 To investigate the relationship between effectiveness and periods of nutrition interventions about infants aged 6~24 months in Ningqiang county. 【Methods】 Infants were divided according to periods of nutrition interventions.And the differences of infants' weight-for-age Z-score(WAZ),height-for-age Z-score(HAZ),weight-for-height Z-score(WHZ)and hemoglobin concentration between groups were compared. 【Results】 The WAZ of 0~2.9 months group,3~5.9 months group and 6~8.9 months group were 0.37±1.25,0.07±0.97,0.07±1.02,respectively,and they increased significantly compared to the baseline(P<0.01).The WHZ of 0~2.9 months group,3~5.9 months group and 6~8.9 months group were 0.55±1.11,0.43±1.00,0.32±1.26,respectively,there were significant differences between intervention groups and non-intervention group.(P<0.01).The HAZ of 0~2.9 months group(P<0.01)and 6~8.9 months group(P<0.05) also increased significantly. 【Conclusions】 Through nutrition interventions the nutrition status of infants aged 6~24 months could be improved significantly.And there is a susceptive periods of nutrition interventions '0~9months'.

Effects of marginal vitamin A deficiency during pregnancy on the lung' morphology of fetal rats

LIU You-hong

2012, 20(5):  416-418. 

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【Objective】 To observe the effects of marginal vitamin A deficiency during pregnancy on the lung' morphology of fetal rats. 【Methods】 Prenatal vitamin A normal(VAN)and marginal vitamin A deficiency(MVAD)of Sprague-Dawley rat models were employed.There were 6 mice in each group.On the gestational day 19,fetal rats were harvested by cesarean section.Then weighed their body,lung and liver.The fetal lung morphology were observed by light microscope after hematoxylin and eosin stain.The vitamin A concentrations of lung were detected by high-performance liquid chromatography(HPLC),and the levels of retinoic acid receptor(RAR)mRNAs were detected by semi-quantitative reverse transcription-polymerase chain reaction(RT-PCR),then the values of RAR mRNAs were compared to glyceraldehyde-3-phosphate dehydrogenase(GAPDH)mRNA. 【Results】 1)The weights of fetals'body,lung and liver in VAN group were higher than those of MVAD group(P<0.05).2)By light microscope(high and lower power lens),the fetal lung morphology were better developed in VAN group than MVAD group.In VAN group,alveolar-like structure were better-arranged,and alveolar septums were thinner.They were rich in blood capillary among the interstitial tissue.They were canalicular period;but MVAD group were gland period.3)Compared with the two groups,the vitamin A concentrations of lungs in VAN group were higher than those of MVAD group(P<0.05).4)The levels of RAR and mRNA in VAN group were lower than those of MVAD group(P<0.05). 【Conclusions】 The weights of fetals' body,lung and liver,the fetal lung morphology,the vitamin A concentrations of lungs and the levels of RAR and mRNA are all influenced by vitamin A level during pregnancy.The fetal lung whose mother are vitamin A deficiency during pregnancy are worse developed.

Study on the early intervention in developmental dysplasia of hip

LI Lin,ZHAO Hong,WANG Feng-mei,LIANG Xiang-li

2012, 20(5):  438-440. 

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【Objective】 To explore the effects of early intervention in developmental dysplasia of hip. 【Methods】 For those,infants under six months who were diagnosed with developmental dysplasia of hip by Color Ultrasonic Doppler,according to the hyper acoustic results and their ages,we enacted different intervening strategies and therapeutic schedules,and also advised their parents conduct early intervention and regular follow-up interview. 【Results】 After these 73 of 122 hip joints of GrafIIa were reexamined and found that 71 of them had return to normal,and the other 2 of no avail also returned to normal after Pavlik hammock treat.8 of 10 of GrafIIb returned to normal after Pavlik hammock treat,and the other 2 also had return to normal after treat in children orthopedics department.2 of 3 hip joints of GrafIIc-IV had return to normal after receiving treat in children orthopedics department,and the other 1 took in an operation after non-effected traditional treat.23 of 41 hip joints without reexamination received X-ray check after six months.2 of them were diagnosed as DDH and back to normal after treat in children orthopedics department.The left 18 refused to take reexamination and another 8 lost contact. 【Conclusion】 Therefore it is concluded that the early intervention in developmental dysplasia of hip will help them progress towards normal hip joint structure.

Long-term longitudinal study of anemia incidence and related factors in 6 to 24 months old infants and young children in Shanghai

GAO Ning,SHENG Xiao-yang,LIU Shen,ZHENG Wen-tao,WEI You-jun,CHEN Xue-ying,YANG Yu-ping

2012, 20(5):  441-443. 

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【Objective】 To observe the anemia incidence and related factors in infants and young children in Shanghai. 【Methods】 Healthy full-term singleton 6 months old infants were recruited and followed.Hemoglobin and red blood cell mass were screened,anthropometric were measured,and feeding information were collected at 6,12,and 24 months old. 【Results】 A total of 189 infants were recruited at 6 months old,149 infants completed the follow-up at 12 months old,and 101 young children completed the follow-up at 24 months old.The incidences of anemia were 18.0%,15.4% and 10.9% at 6,12,24 months old respectively.Most of infants and young children were microcytic anemia.At 6 months old,compared with non-anemia infants,statistically more anemia infants had complementary feeding before 4 months old and without meat at 6 months old (P<0.01). 【Conclusions】 In infants and young children in Shanghai,anemia still existed;the universal hemoglobin screening test might be necessary;iron deficiency,which caused by too early feeding complementary food and too late introduceing meat,is the main reason of anemia.

Study on the diet and nutritional status of rural school-aged children in Anhui province

QIN Feng,ZHONG Li-ru

2012, 20(5):  444-446. 

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【Objective】 To investigate the diet and nutritional status of rural school-aged children in Anhui province,and to provide evidence for the dietary intervention. 【Method】 The nutritional status of the school-aged children were investigated by physical examination and questionnaire survey. 【Results】 The rate of malnutrition in rural school-aged children in Anhui Province was 81.7%,the rate of overweight was 1.8%.Multivariate analysis showed that malnutrition was related to the gender(OR=0.865,P=0.038),grade and the frequency of eating breakfast(OR=1.727,P=0.001);overweight was related to the gender(OR=2.359,P=0.002),parents were not work outside(OR=1.478,P=0.048) and grade. 【Conclusion】 The status of malnutrition are really prevalent among the rural school-aged children,it is extremely necessary to strengthen the nutritional education for school-aged children,enhance pupils' knowledge level,build up a correct and reasonable attitude about nutrition,healthy eating behaviors.

Dynamic variation of incidence of neural tube defects during 2002 to 2010 in Shandong province

ZHOU Feng-rong,LI Ge,CHEN Zhi-xin,ZHANG Peng,FAN Yuan-yuan,HAO Bao-zhen

2012, 20(5):  446-448. 

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【Objective】 To study the variation trend in incidence of neural tube defects (NTDs) during 2002 to 2010 in Shandong Province. 【Methods】 Data were collected by hospital-based monitoring,with women of gestation of 28 weeks to seven days after birth as study subjects.And 642 282 perinates were monitored in the Provincial Birth Defect Monitoring Network in 17 regions all over the province,and 242 cases of NTDs during 2002 to 2010 were recorded and analyzed. 【Results】 Incidence of NTDs was 2.1 per 10 000 in 2010,69.1% reduction from 6.8 per 10 000 in 2002,and yearly average reduction of 13.7%.Incidence of NTDs decreased by 61.1% and 75% in rural and urban areas,respectively,and incidence of spina bifida and encephalocele fell by 70.8% and 80.0%,respectively. 【Conclusions】 Incidence of NTDs showed a falling trend in Shandong province,more decrease in rural areas than in urban areas,and incidences of spina bifida and encephalocele fell faster.Babies with NTDs were in poor birth quality,higher perinatal mortality and poor prognosis.Effective preventive measures and prenatal diagnosis should be strengthened to reduce the occurrences of neural tube defects.

Epidemiological investigation and analysis of relevant factors for iron-deficiency anaemia in infants of Zhongshan city

TANG Jing-jing,ZHANG Cui-mei,FU Si-mao,LIU Yu-ling,OU Jun-bin,HUANG Lian-hong,XU Peng,CHEN Ang,HE Shu-hua

2012, 20(5):  449-451. 

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【Objective】 To discuss the incidence of the different-month-old infants with nutritional iron-deficiency anemia (IDA)and its related factors,and to make more rational strategies of prevention and treatment against iron deficiency. 【Methods】 690 children whose ages were 13~24 months(group A,n=345),25~36 months(group B,n=345) were randomly selected as study subjects.Meanwhile,developing questionnaire surveyed among them. 【Results】 The prevalence rates of IDA were 7.0% in children aged 13~36 months in zhongshan city,The prevalence rates were higher in children aged 13~24 months(IDA 9.7%),than children aged 25~36 months (IDA4.3%).These data showed that there were statistically significant differences (P<0.01) in respectively aged children.The three factors included in feeding behavior were closely correlated to IDA. 【Conclusion】 Correcting the picky habit,and guiding the children's diets appropriately can improve anemia.

Study on the status and influential factors of accidental injury among kindergarten children in Zhuhai

FU Min,XIE Li,FU Xiu-ping,HUANG Jie-hua,GONG Li-hua,WAN Jing-fei

2012, 20(5):  452-455. 

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【Objective】 To explore the current situations and the influential factors of accidental injuries among kindergarten children in Zhuhai in order to provide theoretical basis for better preventive work. 【Methods】 A retrospective survey involved 1 428 parents whose children were between 2~6 years old was conducted among 12 kindergartens drawn out on the randomly stratified cluster basis.From March 2010 to March 2011,the incidences and hazards as well as the types of accidental injuries among these children were thoroughly investigated. 【Results】 The incidences of accidental injuries among kindergarten children in Zhuhai was 53.2%.The most common types of injuries were falls (26.8%),collisions (16.1%),bites and scratches (13.0%).The risk factors of injuries were related to children left-handedness,incorrect education modes of mothers,riding bicycle without mother's supervision,children fidgets,gross earnings per month in a family and glass furniture in the house.The protective factors for such injuries included first-aid box at home,mother's correct understanding of the injuries and the regular inspection of toys. 【Conclusion】 Comprehensive safety measures should be taken to deal with the factors leading to children's accidental injuries in the community.

Analysis of intelligence in students with predominantly inattentive type of attention deficit hyperactivity disorder

ZHOU Ting-ting,XIA Jing-wei,CAO Li-juan,CHEN Li-wen

2012, 20(5):  455-457. 

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【Objective】 To study the intelligence developmental status of students with predominantly inattentive type of attention deficit hyperactivity disorder(ADHD). 【Method】 Using Wechsler Intelligence Scale for Children-Revised(WISC-CR),the intelligence test for 107 students were done with predominantly inattentive type of ADHD. 【Results】 The mean full intelligence quotient(IQ) of 107 students with predominantly inattentive type of ADHD was 97.86±15.01,reaching a normal distribution.And the performance intelligence quotient(PIQ)was much better than the verbal intelligence quotient(VIQ)(P＜0.001).In this population,there were 48 students with large imbalance of verbal and performance IQ,which accounted for 44.86% of the total amount.Most of them (40 cases) showed better performance IQ. 【Conclusions】 There are much more intelligence developmental imbalance in students with predominantly inattentive type of ADHD.When analyzing the results of intelligence test,it is more important to concentrate on the students' performance and subtests score than the IQ results only.

Epidemiologic characteristics of birth defects in Shaanxi province in 2010

WU Xiao-qin,LI Pan,ZHOU Xiao-juan,YANG Yang

2012, 20(5):  460-462. 

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【Objective】 To investigate the incidence and epidemiologic characteristics of birth defects in Shaanxi province,and then to provide scientific evidences for exploring risk factors further. 【Methods】 According to "The Birth Defects Monitoring Program of China",all perinatal infants aged from 28 weeks of gestation to 7 days after birth in 25 monitoring hospitals in Shaanxi province in 2010 were monitored for birth defects,the data were entered by Excel 2003 and analyzed by SPSS 13.0 software. 【Results】 The incidence of birth defects in Shaanxi province in 2010 was 124.1/10⁴,The top five main birth defects were congenital heart diseases,total cleft lip,neural tube defects,polydactyly,congenital hydrocephalus,respectively,The incidence of birth defects in rural areas was significantly higher than that in urban areas (χ²=8.58,P<0.01).There were no significant differences between boys and girls,and the incidence of birth defects was the highest among those pregnant women aged over 35 years(170.5/10⁴).The incidence of birth defects among multiple births was higher than that among singleton. 【Conclusions】 The incidence of birth defect in Shaanxi province is lower than the nationwide average level in 2010.The epidemiologic features are that the incidence of birth defects have significant differences between urban and rural areas,among different age of mother,between singleton and multiple births.The government should attach importance to the primary prevention work of the neural tube defects in rural areas,and take effective measures on women over 35 age and multiple pregnancy.

Monitoring and follow-up of infants with congenital heart disease in Haishu district of Ningbo city

WANG Jing-bo

2012, 20(5):  463-465. 

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【Objective】 To investigate the incidence and prognosis of infants with congenital heart disease (CHD). 【Methods】 There were 8 259 cases about the young children who were full-term live births born in Ningbo Haishu district From 2008 to 2010.221 cases were diagnosed by echocardiography in infants with congenital heart disease,they were regular follow-up tracked. 【Results】 The incidence of infants with congenital heart among the top four respectively were the ventricular septal defect,(accounting for 24.89%),patent foramen ovale (accounting for 22.62%),atrial septal defect with patent ductus arteriosus (accounting for 13.57%),arterial ductus closure and patent foramen ovale (accounting for 13.57%);221 cases of congenital heart disease were diagnosed before their first birthday. 【Conclusion】 Congenital heart disease is an important public health problems,carry out monitoring and follow-up congenital heart disease,could improve quality of life of infants and young children.

Analysis of the growth of small for gestational age babies in Zhabei district

JIN Lei-ping

2012, 20(5):  465-467. 

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【Objective】 To fully understand the occurrence and growth of small for gestational age,(SGA) through the physical development research of the children in the whole district. 【Method】 SGA children collected in the paper through retrospective study and prevalence study. 【Result】 Among the 8 829 examples,SGA morbidity took up 4.67%,SGA of premature single birth took up 54%,premature twin birth took up 62%. 【Conclusion】 Mother's nutrition and antenatal care should be taken to reduce the occurrence of SGA and give more care for SGA postpartum nutrition.

Analysis and countermeasures on the administration of infectious diseases prevention and control in kindergartens in Chaoyang district of Beijing

NIE Ying-zi,YUAN Li,LUO Xiao-hang

2012, 20(5):  467-469. 

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【Objective】 To know the status of administration of infectious diseases prevention and control in kindergartens in Chaoyang district of Beijing,provide basis for making prevention and control measures. 【Method】 A questionnaire about the status of administration of infectious diseases prevention and treatment was conducted in all kindergartens of Chaoyang district,including normal kindergartens and migrant workers' kindergartens. 【Result】 Equipment,disinfection and administration of infectious disease prevention and treatment were inadequate,especially in migrant workers' kindergartens. 【Conclusion】 Guidance and propaganda of administration of infectious disease prevention and treatment should be strengthened in kindergartens,so as to establish effective supervision treatments.

Study on serum calcium,phosphorus,zinc and bone alkaline phosphatase in children with rickets

DONG Hui-min,ZHOU Wen-ying,LUO Min-qi

2012, 20(5):  469-471. 

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【Objective】 To compare the levels of the serum calcium,phosphorus,zinc and bone alkaline phosphatase in 60 different rickets (DR) children with those in 60 cases of healthy children. 【Methods】 All the children were selected in Guangzhou during the same period.The 60 rickets children were divided into three groups according to the severity. 【Results】 The levels of calcium,phosphorus and zinc in moderate and severe DR group were significantly lower than that in the control group;the DR group bone alkaline phosphate level was significantly higher than the healthy group's.(P<0.05).Compared with the mild DR group,moderate and severe DR group had significantly less peripheral blood calcium,phosphorus and zinc,and more bone alkaline phosphatase (P<0.05). 【Conclusion】 Serum bone alkaline phosphatase,combining with the serum calcium,phosphorus,zinc,is a sensitive indicator of the disease rickets.

Effect of Simo decoction,Clostridium butyricum powder in treatment of neonatal asphyxia during perinatal period after feeding intolerance

ZHUO Wen-juan

2012, 20(5):  471-473. 

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【Objective】 To observe the effect of Simo decoction,the condition of intolerant infants under Clostridium butyricum powder in treatment of neonatal asphyxia during perinatal period after feeding. 【Methods】 68 infants selected as cases and were randomly divided into the control group (n=36) and treatment group (n=32) cases with amniotic fluid meconium pollution in two groups were treated with gastric lavage,after gastric lavage they could not open the milk until fasting for 6 hours.The control group received the treatment of Combined Bacillus Subtilis and Enterococcus Faecium Granules with Multivitamines,Live,and the treatment group was treated with the Simo decoction,Clostridium butyricum powder treatment,daily record of vomiting,amount of milk,stool frequency,abdominal distention disappeared days of age,the days of birth weight,such as age of recovery. 【Results】 The experimental group reduced frequency of vomiting ,and vomiting,abdominal distension disappeared ahead of time,up to 50 kCal/(kg·d) days in advance,to restore the birth weight of the days in advance,with statistically significant (P<0.05). 【Conclusion】 The Simo decoction,Clostridium butyricum powder in treatment of neonatal asphyxia during perinatal period after feeding intolerance,can promote gastrointestinal functional maturation,improve feeding tolerance,and it's safe to human beings.

Analysis of supervising results of death for the children under the age of 5 in Liuzhou from 2003 to 2011

LI Hong-hui,NONG Zheng,MO Xu-qun

2012, 20(5):  476-477. 

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【Objectives】 To analyze the death rates and death causes for the children under the age of 5 in Liuzhou from 2003 to 2011 and find out the trends and rules of death causes in children and provide a theoretical basis for the development of the health policies and interventions on reducing the death rates in children under the age of 5. 【Methods】 The death monitoring data of 6 071 cases in the children under the age of 5 were retrospectively analyzed during 2003-2011 in Liuzhou (including six counties and four districts). 【Results】 The nine-year surveillance data showed that the death rates of newborns,infants,and children under the age of 5 mortality rates greatly decreased.In 2011,the death rates for newborns,infants,and children under the age of 5 were 4.58‰,7.43‰ and 9.91‰,respectively.Compared with the death rates of three age groups in 2003,the death rates for newborns,infants,and children under the age of 5 were reduced by 6.91%,9.73% and 10.57%,respectively.The top five death causes for children under the age of 5 were as follows:preterm/low birth weight,congenital heart disease,birth asphyxia,congenital anomalies and accidental death. 【Conclusions】 Strengthening the ability of the child health care grassroots personnel in the appropriate neonatal resuscitation technical training,and vigorously promoting and guiding the knowledge of health care during pregnancy,can effectively reduce the death of children under the age of 5 and the incidence of birth defects.It can also strongly improve the quality of the population.

Investigation and cogitation of status of feeding pets in students'family of three middle and primary schools in Yichang

ZHANG Ping-yu,TAN Ya-fei,LIU Hua-hui,CHEN Xi-lan,DENG Qing

2012, 20(5):  478-480. 

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【Objective】 To investigate the basic status of feeding pets and the recognition of pet-borne diseases among students' family. 【Methods】 Students from three schools were investigated with self-designed questionnaires. 【Results】 31.0% of the investigated families in Yichang had fed pets and the different ratio of the residents keeping pets in different districts and ages had statistical significance.70.4% of the students knew that pets spreaded diseases to person,however only 5.5% of the students knowed definitely how to prevent infecting diseases with their pets.Moreover,senior students holded higher cognitive correctness than lower grade students and the different level of their cognition in different grades had statistical significance. 【Conclusions】 Nowadays a great amount of students' families are keeping pets,but they lack the knowledge of scientific feeding patterns as well as the prevention of infectious diseases.It is indispensable to strengthen the relevant propaganda and education in the communities.