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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2002, Vol. 7 ›› Issue (6): 570-573.

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Progress in animal models of experimental osteoporsis

LIU Yu-Yu, WU Tie, WANG Hui   

  1. Department of Pharmacology,Guangdong Medical College,Zhanjiang 524023
  • Received:2002-08-26 Revised:2002-09-04 Online:2002-12-26 Published:2020-11-20

Abstract: Animals for model of osteoporosis involve rat,mouse,rabbit,beagle dog,minipig,sheep,etc.The types of model include aged-related model,ovariectomized model,orchietomied model,drug-treated model,abolition-degeneration model,and dietary-bone loss.The rat with ovariectomized model is used widely.Biochemical determination,bone mineral density measurement,bone histomorphorphormetry and bone biomechanics are used to judge the formation of experimental osteoporosis.

Key words: osteoporosis, animal model, bone

CLC Number: